Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056522425> ?p ?o ?g. }
- W2056522425 endingPage "560" @default.
- W2056522425 startingPage "550" @default.
- W2056522425 abstract "Walleye dermal sarcoma virus is a complex retrovirus that is associated with walleye dermal sarcomas that are seasonal in nature. Fall developing tumors contain low levels of spliced accessory gene transcripts A and B , suggesting a role for the encoded proteins, Orf A and Orf B, in oncogenesis. In explanted tumor cells the 35 kDa Orf B accessory protein is localized to the cell periphery in structures similar to focal adhesions and along actin stress fibers. Similar localization was observed in mammalian cells. The cellular protein, receptor for activated C kinase 1 (RACK1), bound Orf B in yeast two-hybrid assays and in cell culture. Sequence analysis of walleye RACK1 demonstrated high conservation to other known RACK1 sequences. RACK1 binds to activated protein kinase C (PKC). Orf B associates with PKCα, which is constitutively activated and localized at the membrane. Activated PKC promoted cell survival, proliferation, and increased cell viability in Orf B-expressing cells." @default.
- W2056522425 created "2016-06-24" @default.
- W2056522425 creator A5010828868 @default.
- W2056522425 creator A5027776193 @default.
- W2056522425 creator A5075726784 @default.
- W2056522425 date "2008-06-01" @default.
- W2056522425 modified "2023-09-29" @default.
- W2056522425 title "Walleye dermal sarcoma virus Orf B functions through receptor for activated C kinase (RACK1) and protein kinase C" @default.
- W2056522425 cites W1495423595 @default.
- W2056522425 cites W1500453171 @default.
- W2056522425 cites W1517614087 @default.
- W2056522425 cites W1532711865 @default.
- W2056522425 cites W1554882994 @default.
- W2056522425 cites W1576671418 @default.
- W2056522425 cites W1755902553 @default.
- W2056522425 cites W1815010795 @default.
- W2056522425 cites W1864792737 @default.
- W2056522425 cites W1964839077 @default.
- W2056522425 cites W1966478905 @default.
- W2056522425 cites W1967122562 @default.
- W2056522425 cites W1968167396 @default.
- W2056522425 cites W1969063564 @default.
- W2056522425 cites W1969150166 @default.
- W2056522425 cites W1973046803 @default.
- W2056522425 cites W1977866485 @default.
- W2056522425 cites W1983649171 @default.
- W2056522425 cites W1983755623 @default.
- W2056522425 cites W1986797405 @default.
- W2056522425 cites W1991714532 @default.
- W2056522425 cites W1992592847 @default.
- W2056522425 cites W1993282564 @default.
- W2056522425 cites W1994619600 @default.
- W2056522425 cites W1996546475 @default.
- W2056522425 cites W1998490733 @default.
- W2056522425 cites W1999987807 @default.
- W2056522425 cites W2014969594 @default.
- W2056522425 cites W2022178223 @default.
- W2056522425 cites W2022198735 @default.
- W2056522425 cites W2024170705 @default.
- W2056522425 cites W2029352353 @default.
- W2056522425 cites W2029694902 @default.
- W2056522425 cites W2033686476 @default.
- W2056522425 cites W2041203055 @default.
- W2056522425 cites W2041556575 @default.
- W2056522425 cites W2044113269 @default.
- W2056522425 cites W2046111296 @default.
- W2056522425 cites W2050135377 @default.
- W2056522425 cites W2050600731 @default.
- W2056522425 cites W2052434326 @default.
- W2056522425 cites W2052720758 @default.
- W2056522425 cites W2065291280 @default.
- W2056522425 cites W2072460704 @default.
- W2056522425 cites W2077673061 @default.
- W2056522425 cites W2099182237 @default.
- W2056522425 cites W2101836788 @default.
- W2056522425 cites W2105251750 @default.
- W2056522425 cites W2109519875 @default.
- W2056522425 cites W2122054605 @default.
- W2056522425 cites W2123626707 @default.
- W2056522425 cites W2125711915 @default.
- W2056522425 cites W2129029860 @default.
- W2056522425 cites W2131530858 @default.
- W2056522425 cites W2138532817 @default.
- W2056522425 cites W2151067385 @default.
- W2056522425 cites W2157983485 @default.
- W2056522425 cites W2160332942 @default.
- W2056522425 cites W2169819991 @default.
- W2056522425 cites W2172203795 @default.
- W2056522425 cites W2325747908 @default.
- W2056522425 cites W2327883130 @default.
- W2056522425 cites W2338069231 @default.
- W2056522425 doi "https://doi.org/10.1016/j.virol.2008.01.034" @default.
- W2056522425 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2453751" @default.
- W2056522425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18343476" @default.
- W2056522425 hasPublicationYear "2008" @default.
- W2056522425 type Work @default.
- W2056522425 sameAs 2056522425 @default.
- W2056522425 citedByCount "17" @default.
- W2056522425 countsByYear W20565224252012 @default.
- W2056522425 countsByYear W20565224252014 @default.
- W2056522425 countsByYear W20565224252015 @default.
- W2056522425 countsByYear W20565224252016 @default.
- W2056522425 countsByYear W20565224252018 @default.
- W2056522425 countsByYear W20565224252019 @default.
- W2056522425 countsByYear W20565224252021 @default.
- W2056522425 countsByYear W20565224252022 @default.
- W2056522425 countsByYear W20565224252023 @default.
- W2056522425 crossrefType "journal-article" @default.
- W2056522425 hasAuthorship W2056522425A5010828868 @default.
- W2056522425 hasAuthorship W2056522425A5027776193 @default.
- W2056522425 hasAuthorship W2056522425A5075726784 @default.
- W2056522425 hasBestOaLocation W20565224252 @default.
- W2056522425 hasConcept C104317684 @default.
- W2056522425 hasConcept C153911025 @default.
- W2056522425 hasConcept C159047783 @default.
- W2056522425 hasConcept C184235292 @default.
- W2056522425 hasConcept C2522874641 @default.
- W2056522425 hasConcept C2778431562 @default.