FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056523105> ?p ?o ?g. }

• W2056523105 endingPage "1194" @default.
• W2056523105 startingPage "1190" @default.
• W2056523105 abstract "Sepsis and endotoxemia are associated with increased muscle protein breakdown and inhibited amino acid uptake. Glucocorticoids are important for the regulation of muscle protein breakdown in catabolic conditions; in contrast, the role of glucocorticoids in the regulation of muscle amino acid transport during sepsis or endotoxemia is not known. The present study was designed to test the role of glucocorticoids in the regulation of muscle amino acid uptake during endotoxemia. Amino acid transport, determined as uptake of 3H-alpha-aminoisobutyric acid (AIB) by incubated soleus muscles in vitro, was reduced by approximately 40% 2 hours after intraperitoneal (IP) injection of 10 micrograms/kg endotoxin in rats. Administration of 5 mg/kg of the glucocorticoid receptor antagonist RU 38486 2 hours before endotoxin injection did not affect the inhibition of amino acid uptake. In vitro addition of plasma from endotoxemic rats to incubated rat soleus muscles inhibited amino acid uptake by approximately 30%. This effect of endotoxic plasma also was noted when muscles were from rats that had been treated with RU 38486 and when RU 38486 was present in the incubation medium. Results confirm previous reports of reduced muscle amino acid transport during endotoxemia and of the presence of a circulating factor that inhibits muscle amino acid uptake in this condition. Data suggest that inhibited muscle amino acid transport during endotoxemia is not regulated by glucocorticoids." @default.
• W2056523105 created "2016-06-24" @default.
• W2056523105 creator A5007080085 @default.
• W2056523105 creator A5072508720 @default.
• W2056523105 creator A5073095140 @default.
• W2056523105 creator A5085972527 @default.
• W2056523105 date "1993-09-01" @default.
• W2056523105 modified "2023-09-29" @default.
• W2056523105 title "Evidence that inhibition of muscle amino acid uptake during endotoxemia is not mediated by glucocorticoids" @default.
• W2056523105 cites W1515927821 @default.
• W2056523105 cites W1972887072 @default.
• W2056523105 cites W1975783493 @default.
• W2056523105 cites W1986249600 @default.
• W2056523105 cites W1989579475 @default.
• W2056523105 cites W2000152465 @default.
• W2056523105 cites W2037288998 @default.
• W2056523105 cites W2056984312 @default.
• W2056523105 cites W2057582430 @default.
• W2056523105 cites W2062493213 @default.
• W2056523105 cites W2066598465 @default.
• W2056523105 cites W2142156643 @default.
• W2056523105 cites W2145118081 @default.
• W2056523105 cites W2164391294 @default.
• W2056523105 cites W2177210292 @default.
• W2056523105 cites W2211031122 @default.
• W2056523105 cites W2253986594 @default.
• W2056523105 cites W2282085055 @default.
• W2056523105 cites W2297940787 @default.
• W2056523105 cites W2338212033 @default.
• W2056523105 cites W2399110598 @default.
• W2056523105 cites W2415700488 @default.
• W2056523105 cites W2461178314 @default.
• W2056523105 cites W2496954960 @default.
• W2056523105 cites W2599880923 @default.
• W2056523105 cites W425268794 @default.
• W2056523105 doi "https://doi.org/10.1016/0026-0495(93)90279-w" @default.
• W2056523105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8412774" @default.
• W2056523105 hasPublicationYear "1993" @default.
• W2056523105 type Work @default.
• W2056523105 sameAs 2056523105 @default.
• W2056523105 citedByCount "5" @default.
• W2056523105 crossrefType "journal-article" @default.
• W2056523105 hasAuthorship W2056523105A5007080085 @default.
• W2056523105 hasAuthorship W2056523105A5072508720 @default.
• W2056523105 hasAuthorship W2056523105A5073095140 @default.
• W2056523105 hasAuthorship W2056523105A5085972527 @default.
• W2056523105 hasConcept C126322002 @default.
• W2056523105 hasConcept C134018914 @default.
• W2056523105 hasConcept C170493617 @default.
• W2056523105 hasConcept C185592680 @default.
• W2056523105 hasConcept C197683979 @default.
• W2056523105 hasConcept C202751555 @default.
• W2056523105 hasConcept C2776104385 @default.
• W2056523105 hasConcept C2776885963 @default.
• W2056523105 hasConcept C2778384902 @default.
• W2056523105 hasConcept C2779959927 @default.
• W2056523105 hasConcept C2780004078 @default.
• W2056523105 hasConcept C2780841215 @default.
• W2056523105 hasConcept C515207424 @default.
• W2056523105 hasConcept C55493867 @default.
• W2056523105 hasConcept C59493245 @default.
• W2056523105 hasConcept C62231903 @default.
• W2056523105 hasConcept C71924100 @default.
• W2056523105 hasConcept C86803240 @default.
• W2056523105 hasConcept C96942376 @default.
• W2056523105 hasConceptScore W2056523105C126322002 @default.
• W2056523105 hasConceptScore W2056523105C134018914 @default.
• W2056523105 hasConceptScore W2056523105C170493617 @default.
• W2056523105 hasConceptScore W2056523105C185592680 @default.
• W2056523105 hasConceptScore W2056523105C197683979 @default.
• W2056523105 hasConceptScore W2056523105C202751555 @default.
• W2056523105 hasConceptScore W2056523105C2776104385 @default.
• W2056523105 hasConceptScore W2056523105C2776885963 @default.
• W2056523105 hasConceptScore W2056523105C2778384902 @default.
• W2056523105 hasConceptScore W2056523105C2779959927 @default.
• W2056523105 hasConceptScore W2056523105C2780004078 @default.
• W2056523105 hasConceptScore W2056523105C2780841215 @default.
• W2056523105 hasConceptScore W2056523105C515207424 @default.
• W2056523105 hasConceptScore W2056523105C55493867 @default.
• W2056523105 hasConceptScore W2056523105C59493245 @default.
• W2056523105 hasConceptScore W2056523105C62231903 @default.
• W2056523105 hasConceptScore W2056523105C71924100 @default.
• W2056523105 hasConceptScore W2056523105C86803240 @default.
• W2056523105 hasConceptScore W2056523105C96942376 @default.
• W2056523105 hasIssue "9" @default.
• W2056523105 hasLocation W20565231051 @default.
• W2056523105 hasLocation W20565231052 @default.
• W2056523105 hasOpenAccess W2056523105 @default.
• W2056523105 hasPrimaryLocation W20565231051 @default.
• W2056523105 hasRelatedWork W1642498015 @default.
• W2056523105 hasRelatedWork W1971750897 @default.
• W2056523105 hasRelatedWork W1979346277 @default.
• W2056523105 hasRelatedWork W2015141992 @default.
• W2056523105 hasRelatedWork W2020444746 @default.
• W2056523105 hasRelatedWork W2033203645 @default.
• W2056523105 hasRelatedWork W2056523105 @default.
• W2056523105 hasRelatedWork W2078471485 @default.
• W2056523105 hasRelatedWork W2098663397 @default.

• next