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- W2056524701 abstract "The in vitro carcinogenesis assay developed by Pienta was statistically evaluated. Transformation assay of 3-methylcholanthrene (3MC) and solvent control were repeated 8 times. There was no transformation in controls and 3MC induced 7.38 transformed colonies as an average. Fitting the binomial distribution the possibility to take a false negative was calculated. It is concluded that the positive result is highly reliable but there is considerably high risk to take a false negative unless experiments are repeated." @default.
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- W2056524701 date "1978-05-01" @default.
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- W2056524701 title "Statistical evaluation of Pienta's in vitro carcinogenesis assay" @default.
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- W2056524701 doi "https://doi.org/10.1016/0378-4274(78)90060-7" @default.
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