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- W2056528958 abstract "Electrocardiographic (ECG) abnormalities are common following transthoracic defibrillation. ECG ST segment changes are especially problematic following defibrillation and may indicate ischemia or shock induced cardiac dysfunction after resuscitation. Biphasic defibrillation waveforms, compared to monophasic waveforms. diminish shock-induced cardiac dysfunction in laboratory preparations. This effect has not been validated in man. Therefore. we evaluated in a prospective. blinded fashion, the effect of biphasic and monophasic transthoracic defibrillation on the ECG ST segment in 30 consecutive patients during implantable cardioverter-defibrillator surgery. In each patient two low energy truncated biphasic transthoracic defibrillation shocks were compared to the standard 200 J monophasic damped sine wave shock traditionally employed in transthoracic defibrillators. Both biphasic shocks and the damped sine wave shock have previously demonstrated equal efficacies of 97%. Fifteen second bipolar ECG signals recorded across transthoracic defibrillation electrodes were digitized prior to ventricular fibrillation induction (baseline) and immediately after each defibrillation attempt. These signals were printed. and the STsegments analyzed in a blinded fashion by two reviewers. ST segment deflection (10 mm/mV) after therapy was compared to the baseline ST segment deflection for each of the dafibrillation waveforms used. Changes in the absolute value of the ST segment level were significantly greater with the 200 J damped sine waveform than with either biphasic waveform:WaveformECG ST segment change (mm)115 J Blphasic0.73 ± 0.62130 J Biphasic081 ± 0.24200 J Damped Sine2.10 ± 1.94**p < 0.0001 p < 0.0001 Transthoracic defibrillation with biphasic waveforms results in less post-shock ECG evidence of myocardial dysfunction (injury or ischemia) compared to the standard damped sine waveform without compromising defibrillation efficacy." @default.
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- W2056528958 date "1995-02-01" @default.
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- W2056528958 title "1025-95 Biphasic Truncated Waveform Transthoracic Defibrillation Results in Less Post-shock ECG ST Segment Changes than Standard Damped Sine Wave Shocks" @default.
- W2056528958 doi "https://doi.org/10.1016/0735-1097(95)93139-4" @default.
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