FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056529290> ?p ?o ?g. }

• W2056529290 endingPage "423" @default.
• W2056529290 startingPage "421" @default.
• W2056529290 abstract "Background Luer-activated devices (LAD) have been designed to reduce the risk of sharps injury; however, published reports suggest that internal fluid path contamination occurs in selected devices. The present in vitro study compares the antimicrobial property of a silver-nanotechnology LAD to 8 nonantimicrobial LADs. Methods A laboratory reference strain of methicillin-resistant Staphylococcus aureus (MRSA) (ATCC 33592) was used to prepare a standardized microbial challenge, 3.73- to 3.86-log10 colony-forming units (cfu)/mL, adjusted for fluid path volume for 9 commercially available LAD (1 sliver nanotechnology LAD and 8 non-antimicrobial LADs). Following incubation (15 hours at 30°C), each device was flushed, serially diluted, and plated in triplicate to trypticase soy agar for microbial recovery, expressed as log10 cfu/mL. Results Comparison of fluid path volumes documented a wide variation between the 9 commercial devices (range, 0.025-0.359 mL). Log10 microbial recovery were shown to increase on average 1.5 to 3.0 logs in the 8 non-antimicrobial LADs, whereas S aureus recovery in the silver-nanoparticle LAD demonstrated a 2.6-log decrease following incubation (P ≤ .05). Conclusion These findings suggest that, under in vitro conditions, a silver nanotechnology was effective in reducing the risk of fluid path colonization when the LAD was challenged using a standardized inoculum of a laboratory reference strain of MRSA. Further studies are warranted to assess the clinical efficacy of an antimicrobial LAD technology for reducing the risk of vascular access (catheter associated) infections. Luer-activated devices (LAD) have been designed to reduce the risk of sharps injury; however, published reports suggest that internal fluid path contamination occurs in selected devices. The present in vitro study compares the antimicrobial property of a silver-nanotechnology LAD to 8 nonantimicrobial LADs. A laboratory reference strain of methicillin-resistant Staphylococcus aureus (MRSA) (ATCC 33592) was used to prepare a standardized microbial challenge, 3.73- to 3.86-log10 colony-forming units (cfu)/mL, adjusted for fluid path volume for 9 commercially available LAD (1 sliver nanotechnology LAD and 8 non-antimicrobial LADs). Following incubation (15 hours at 30°C), each device was flushed, serially diluted, and plated in triplicate to trypticase soy agar for microbial recovery, expressed as log10 cfu/mL. Comparison of fluid path volumes documented a wide variation between the 9 commercial devices (range, 0.025-0.359 mL). Log10 microbial recovery were shown to increase on average 1.5 to 3.0 logs in the 8 non-antimicrobial LADs, whereas S aureus recovery in the silver-nanoparticle LAD demonstrated a 2.6-log decrease following incubation (P ≤ .05). These findings suggest that, under in vitro conditions, a silver nanotechnology was effective in reducing the risk of fluid path colonization when the LAD was challenged using a standardized inoculum of a laboratory reference strain of MRSA. Further studies are warranted to assess the clinical efficacy of an antimicrobial LAD technology for reducing the risk of vascular access (catheter associated) infections." @default.
• W2056529290 created "2016-06-24" @default.
• W2056529290 creator A5014575450 @default.
• W2056529290 creator A5087800012 @default.
• W2056529290 date "2010-08-01" @default.
• W2056529290 modified "2023-09-27" @default.
• W2056529290 title "Reducing the risk of infection in vascular access patients: An in vitro evaluation of an antimicrobial silver nanotechnology luer activated device" @default.
• W2056529290 cites W1964633276 @default.
• W2056529290 cites W1986302632 @default.
• W2056529290 cites W1988723216 @default.
• W2056529290 cites W1994373559 @default.
• W2056529290 cites W2003114988 @default.
• W2056529290 cites W2010426443 @default.
• W2056529290 cites W2022601280 @default.
• W2056529290 cites W2030660025 @default.
• W2056529290 cites W2036611632 @default.
• W2056529290 cites W2038898817 @default.
• W2056529290 cites W2042785780 @default.
• W2056529290 cites W2078636110 @default.
• W2056529290 cites W2113420106 @default.
• W2056529290 cites W2127311884 @default.
• W2056529290 cites W2131141897 @default.
• W2056529290 cites W2151046640 @default.
• W2056529290 cites W2162004715 @default.
• W2056529290 doi "https://doi.org/10.1016/j.ajic.2009.09.010" @default.
• W2056529290 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20189684" @default.
• W2056529290 hasPublicationYear "2010" @default.
• W2056529290 type Work @default.
• W2056529290 sameAs 2056529290 @default.
• W2056529290 citedByCount "10" @default.
• W2056529290 countsByYear W20565292902013 @default.
• W2056529290 countsByYear W20565292902014 @default.
• W2056529290 countsByYear W20565292902015 @default.
• W2056529290 countsByYear W20565292902017 @default.
• W2056529290 countsByYear W20565292902019 @default.
• W2056529290 crossrefType "journal-article" @default.
• W2056529290 hasAuthorship W2056529290A5014575450 @default.
• W2056529290 hasAuthorship W2056529290A5087800012 @default.
• W2056529290 hasConcept C141071460 @default.
• W2056529290 hasConcept C25642318 @default.
• W2056529290 hasConcept C2777399836 @default.
• W2056529290 hasConcept C2779489039 @default.
• W2056529290 hasConcept C2781267111 @default.
• W2056529290 hasConcept C4937899 @default.
• W2056529290 hasConcept C523546767 @default.
• W2056529290 hasConcept C54355233 @default.
• W2056529290 hasConcept C55493867 @default.
• W2056529290 hasConcept C71924100 @default.
• W2056529290 hasConcept C86803240 @default.
• W2056529290 hasConcept C89423630 @default.
• W2056529290 hasConceptScore W2056529290C141071460 @default.
• W2056529290 hasConceptScore W2056529290C25642318 @default.
• W2056529290 hasConceptScore W2056529290C2777399836 @default.
• W2056529290 hasConceptScore W2056529290C2779489039 @default.
• W2056529290 hasConceptScore W2056529290C2781267111 @default.
• W2056529290 hasConceptScore W2056529290C4937899 @default.
• W2056529290 hasConceptScore W2056529290C523546767 @default.
• W2056529290 hasConceptScore W2056529290C54355233 @default.
• W2056529290 hasConceptScore W2056529290C55493867 @default.
• W2056529290 hasConceptScore W2056529290C71924100 @default.
• W2056529290 hasConceptScore W2056529290C86803240 @default.
• W2056529290 hasConceptScore W2056529290C89423630 @default.
• W2056529290 hasIssue "6" @default.
• W2056529290 hasLocation W20565292901 @default.
• W2056529290 hasLocation W20565292902 @default.
• W2056529290 hasOpenAccess W2056529290 @default.
• W2056529290 hasPrimaryLocation W20565292901 @default.
• W2056529290 hasRelatedWork W1784239895 @default.
• W2056529290 hasRelatedWork W1839011430 @default.
• W2056529290 hasRelatedWork W2015539383 @default.
• W2056529290 hasRelatedWork W2048267026 @default.
• W2056529290 hasRelatedWork W2082480737 @default.
• W2056529290 hasRelatedWork W2753184995 @default.
• W2056529290 hasRelatedWork W2954159082 @default.
• W2056529290 hasRelatedWork W3037491291 @default.
• W2056529290 hasRelatedWork W4213320541 @default.
• W2056529290 hasRelatedWork W2894777053 @default.
• W2056529290 hasVolume "38" @default.
• W2056529290 isParatext "false" @default.
• W2056529290 isRetracted "false" @default.
• W2056529290 magId "2056529290" @default.
• W2056529290 workType "article" @default.