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• W2056533289 abstract "Mesoporous nanosized hydroxyapatite (HAP) functionalized by alendronate (ALN) was synthesized using cationic surfactant CTAB as template. The structural, morphological and textural properties were fully characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR) and N2 adsorption/desorption. Then the obtained materials were performed as drug delivery carriers using ibuprofen (IBU) as a model drug to investigate their drug storage/release properties in simulated body fluid (SBF). The materials showed relatively slower release rate compared with HAP due to the ionic interaction between NH3+ on the matrix and COO−belongs to IBU. The system provides a new concept for improving the drug loading or slowing down the release rate." @default.
• W2056533289 created "2016-06-24" @default.
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• W2056533289 date "2013-06-01" @default.
• W2056533289 modified "2023-09-23" @default.
• W2056533289 title "Alendronate functionalized mesoporous hydroxyapatite nanoparticles for drug delivery" @default.
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• W2056533289 doi "https://doi.org/10.1016/j.materresbull.2013.02.049" @default.
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