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- W2056534064 abstract "We report analysis of the NaCl-induced B-Z transition in a 16 base-pair duplex DNA with sequence designed such that when NaCl is increased the left half of the molecule undergoes the B-Z transition while the right half remains in the B-form. An equilibrium thermodynamic model based on the body of available published experimental data and the recent theoretical work of Soumpasis, which indicate, in the salt range above ~0.9 m-NaCl, the transition free-energy of B-Z conversion in DNA is a linear function of the NaCl concentration, is employed. Analysis of the B-Z transition of the junction-containing molecule indicates the B-Z junction formed in this 16 base-pair DNA is composed of approximately three base-pairs and has a free energy of formation of ~4.7 kcal/mol junction. These values for the junction are in excellent agreement with published estimates of B-Z junction size and energy derived from much longer DNA pieces." @default.
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- W2056534064 date "1990-03-01" @default.
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- W2056534064 title "Energetics of B-Z junction formation in a sixteen base-pair duplex DNA" @default.
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- W2056534064 doi "https://doi.org/10.1016/0022-2836(90)90297-y" @default.
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