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- W2056536905 abstract "The excellent early results of coronary artery bypass grafting (CABG) are limited in the long term by vein graft failure. Ten years after CABG 50% of vein conduits are occluded or severely diseased, whereas more than 90% of internal thoracic artery (ITA) grafts are patent and disease-free. Because of this, total arterial revascularization has been advocated to avoid use of vein grafts and their subsequent suboptimal fate. The pathology of vein graft disease consists of thrombosis, neointimal hyperplasia (NeoH), and vein graft atherosclerosis which affect graft permeability and longevity. Indeed, vein graft failure leads to decreased survival, recurrent angina, late myocardial infarction, and the need for further intervention. Aspirin and lipid-lowering agents improve vein graft patency rates over the medium term, but their effect on long-term results are unknown. New approaches are being developed to preserve vein graft patency over time." @default.
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- W2056536905 date "2012-11-01" @default.
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- W2056536905 title "Prevention of Venous Graft Disease After Coronary Artery Bypass Grafting: Is Ex Vivo Statin Exposure an Answer?" @default.
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- W2056536905 doi "https://doi.org/10.1016/j.cjca.2012.04.016" @default.
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