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- W2056536994 abstract "Among the great variety of natural products, found in plants, algae and sea sponge, we can find compounds that have a quinonic/hydroquinonic moiety united to a terpenic skeleton. Natural (-)- cyclozonarone (1), is a drimanic benzoquinone derivative isolated from algae Dintyopteris undulata that posseses a powerful feeding-deterrant activity towards young abalones furthermore shows anticancer activity. The absolute configuration of 1 was establish through a six-step route, starting from natural (-) polygodial, leading us to the synthetic enantiomer (+)-cyclozonarone (2), that showed antileshmania activity. Later, (-)-cyclozonarone was synthesized starting from (+)-albicanol. Both routes of synthesis were based on the Diels-Alder reaction." @default.
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- W2056536994 date "2013-09-01" @default.
- W2056536994 modified "2023-10-16" @default.
- W2056536994 title "Synthesis, citotoxicity activity of new Cyclozonarone angular isomer" @default.
- W2056536994 doi "https://doi.org/10.5151/chempro-14bmos-r0376-1" @default.
- W2056536994 hasPublicationYear "2013" @default.
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