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- W2056539144 abstract "Fast and efficient: A library of trans-cyclooctene (TCO)-modified small molecules were immobilized on tetrazine-functionalized glass slides by using the fastest bioorthogonal reaction known. The resulting small-molecule microarray was screened against a variety of human bromodomains to identify protein–protein interaction inhibitors. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
- W2056539144 created "2016-06-24" @default.
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- W2056539144 date "2013-11-04" @default.
- W2056539144 modified "2023-10-18" @default.
- W2056539144 title "Preparation of Small-Molecule Microarrays by<i>trans</i>-Cyclooctene Tetrazine Ligation and Their Application in the High-Throughput Screening of Protein-Protein Interaction Inhibitors of Bromodomains" @default.
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- W2056539144 doi "https://doi.org/10.1002/anie.201307803" @default.
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