FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056539263> ?p ?o ?g. }

• W2056539263 abstract "Genetically engineered mouse models of mammary gland cancer enable the in vivo study of molecular mechanisms and signaling during development and cancer pathophysiology. However, traditional whole mount and histological imaging modalities are only applicable to non-viable tissue. We evaluated three techniques that can be quickly applied to living tissue for imaging normal and cancerous mammary gland: reflectance confocal microscopy, green fluorescent protein imaging, and ultrasound imaging. In the current study, reflectance confocal imaging offered the highest resolution and was used to optically section mammary ductal structures in the whole mammary gland. Glands remained viable in mammary gland whole organ culture when 1% acetic acid was used as a contrast agent. Our application of using green fluorescent protein expressing transgenic mice in our study allowed for whole mammary gland ductal structures imaging and enabled straightforward serial imaging of mammary gland ducts in whole organ culture to visualize the growth and differentiation process. Ultrasound imaging showed the lowest resolution. However, ultrasound was able to detect mammary preneoplastic lesions 0.2 mm in size and was used to follow cancer growth with serial imaging in living mice. In conclusion, each technique enabled serial imaging of living mammary tissue and visualization of growth and development, quickly and with minimal tissue preparation. The use of the higher resolution reflectance confocal and green fluorescent protein imaging techniques and lower resolution ultrasound were complementary." @default.
• W2056539263 created "2016-06-24" @default.
• W2056539263 creator A5030889614 @default.
• W2056539263 creator A5037103180 @default.
• W2056539263 creator A5053625755 @default.
• W2056539263 creator A5073725946 @default.
• W2056539263 creator A5080700646 @default.
• W2056539263 creator A5087878110 @default.
• W2056539263 date "2008-01-23" @default.
• W2056539263 modified "2023-09-27" @default.
• W2056539263 title "Comparison of mouse mammary gland imaging techniques and applications: Reflectance confocal microscopy, GFP Imaging, and ultrasound" @default.
• W2056539263 cites W150683114 @default.
• W2056539263 cites W1516928347 @default.
• W2056539263 cites W1545968958 @default.
• W2056539263 cites W1577816919 @default.
• W2056539263 cites W1945075873 @default.
• W2056539263 cites W1966687379 @default.
• W2056539263 cites W1967963872 @default.
• W2056539263 cites W1985193538 @default.
• W2056539263 cites W1993049724 @default.
• W2056539263 cites W2000743922 @default.
• W2056539263 cites W2018156670 @default.
• W2056539263 cites W2019108544 @default.
• W2056539263 cites W2034035360 @default.
• W2056539263 cites W2038226174 @default.
• W2056539263 cites W2043489363 @default.
• W2056539263 cites W2047887335 @default.
• W2056539263 cites W2048147909 @default.
• W2056539263 cites W2054393119 @default.
• W2056539263 cites W2065825082 @default.
• W2056539263 cites W2070276211 @default.
• W2056539263 cites W2072410176 @default.
• W2056539263 cites W2073447587 @default.
• W2056539263 cites W2074776364 @default.
• W2056539263 cites W2076923434 @default.
• W2056539263 cites W2077211596 @default.
• W2056539263 cites W2085910383 @default.
• W2056539263 cites W2093422961 @default.
• W2056539263 cites W2093516870 @default.
• W2056539263 cites W2096031499 @default.
• W2056539263 cites W2098142970 @default.
• W2056539263 cites W2101817861 @default.
• W2056539263 cites W2108447763 @default.
• W2056539263 cites W2109261171 @default.
• W2056539263 cites W2117329770 @default.
• W2056539263 cites W2119507443 @default.
• W2056539263 cites W2123518031 @default.
• W2056539263 cites W2128335950 @default.
• W2056539263 cites W2131199218 @default.
• W2056539263 cites W2134318982 @default.
• W2056539263 cites W2136175469 @default.
• W2056539263 cites W2144227216 @default.
• W2056539263 cites W2146129028 @default.
• W2056539263 cites W2153062028 @default.
• W2056539263 cites W2154045348 @default.
• W2056539263 cites W2159938531 @default.
• W2056539263 cites W2324020016 @default.
• W2056539263 cites W33280991 @default.
• W2056539263 doi "https://doi.org/10.1186/1471-2407-8-21" @default.
• W2056539263 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2266934" @default.
• W2056539263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18215290" @default.
• W2056539263 hasPublicationYear "2008" @default.
• W2056539263 type Work @default.
• W2056539263 sameAs 2056539263 @default.
• W2056539263 citedByCount "13" @default.
• W2056539263 countsByYear W20565392632012 @default.
• W2056539263 countsByYear W20565392632013 @default.
• W2056539263 countsByYear W20565392632018 @default.
• W2056539263 crossrefType "journal-article" @default.
• W2056539263 hasAuthorship W2056539263A5030889614 @default.
• W2056539263 hasAuthorship W2056539263A5037103180 @default.
• W2056539263 hasAuthorship W2056539263A5053625755 @default.
• W2056539263 hasAuthorship W2056539263A5073725946 @default.
• W2056539263 hasAuthorship W2056539263A5080700646 @default.
• W2056539263 hasAuthorship W2056539263A5087878110 @default.
• W2056539263 hasBestOaLocation W20565392631 @default.
• W2056539263 hasConcept C121332964 @default.
• W2056539263 hasConcept C121608353 @default.
• W2056539263 hasConcept C126322002 @default.
• W2056539263 hasConcept C126838900 @default.
• W2056539263 hasConcept C136009344 @default.
• W2056539263 hasConcept C136339569 @default.
• W2056539263 hasConcept C142724271 @default.
• W2056539263 hasConcept C143409427 @default.
• W2056539263 hasConcept C143753070 @default.
• W2056539263 hasConcept C150903083 @default.
• W2056539263 hasConcept C207001950 @default.
• W2056539263 hasConcept C2524010 @default.
• W2056539263 hasConcept C2776410896 @default.
• W2056539263 hasConcept C2778001805 @default.
• W2056539263 hasConcept C2779178360 @default.
• W2056539263 hasConcept C29331040 @default.
• W2056539263 hasConcept C33923547 @default.
• W2056539263 hasConcept C530470458 @default.
• W2056539263 hasConcept C57477423 @default.
• W2056539263 hasConcept C62520636 @default.
• W2056539263 hasConcept C71924100 @default.
• W2056539263 hasConcept C86803240 @default.
• W2056539263 hasConcept C91881484 @default.
• W2056539263 hasConcept C95444343 @default.

• next