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- W2056540899 abstract "β-Lactam antibiotics, moxalactam (LMOX), cefotaxime (CTX), flomoxef (FMOX), cefamandole (CMD), carbenicillin (CBPC) and sulbenicillin (SBPC), suppressed colony formation from human megakaryocyte progenitors (CFU-M) and granulocyte-macrophage progenitors (CFU-GM) dose-dependently. The suppressive potencies for both progenitors were weakest for CBPC and SBPC, moderate for LMOX and FMOX, and strongest for CMD and CTX. The stainability of glycoprotein llb/llla complex in the megakaryocyte colonies by the monoclonal antibody was decreased by LMOX and CTX. These data suggest that β-lactam antibiotics directly suppress proliferation of CFU-M and CFU-GM." @default.
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- W2056540899 date "1987-01-01" @default.
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- W2056540899 title "Suppressive effect of antibiotics on colony formation from human megakaryocyte progenitors (CFU-M) and granulocyte-macrophage progenitors (CFU-GM)." @default.
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- W2056540899 doi "https://doi.org/10.1254/jjp.43.423" @default.
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