FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056542903> ?p ?o ?g. }

• W2056542903 endingPage "9113" @default.
• W2056542903 startingPage "9109" @default.
• W2056542903 abstract "Electronic polymers in aqueous media offer bioelectronic detection of biomolecular processes. Here we report fluorometric detection of calcium-induced conformational changes in calmodulin based on noncovalent assembly of calmodulin to a water-soluble zwitterionic polythiophene derivative. Assembly with calmodulin will induce a planar geometry and aggregation of the polymer chains, detected as a decrease of the intensity and a red shift of the fluorescence. Upon addition of Ca2+ the intensity of the emitted light is increased and blue-shifted. The geometrical alteration of the polymer chains can further be utilized for recording of the binding of calcineurin to the calcium-activated POWT−calmodulin complex. This novel methodology, using a conformation-sensitive probe, allows fluorometric detection of conformational changes in biomolecules and protein−protein interactions without any covalent modifications of the biomolecules. The rapid and selective method is based on noncovalent interactions between a zwitterionic polythiophene derivative and the biomolecule of interest. This offers a novel way to create microarrays without using covalent attachment of the receptor or labeling of the analyte." @default.
• W2056542903 created "2016-06-24" @default.
• W2056542903 creator A5069932768 @default.
• W2056542903 creator A5086283473 @default.
• W2056542903 date "2004-10-21" @default.
• W2056542903 modified "2023-10-17" @default.
• W2056542903 title "Optical Emission of a Conjugated Polyelectrolyte: Calcium-Induced Conformational Changes in Calmodulin and Calmodulin−Calcineurin Interactions" @default.
• W2056542903 cites W1994902235 @default.
• W2056542903 cites W2007863706 @default.
• W2056542903 cites W2008670090 @default.
• W2056542903 cites W2010424836 @default.
• W2056542903 cites W2015663509 @default.
• W2056542903 cites W2034736217 @default.
• W2056542903 cites W2041414200 @default.
• W2056542903 cites W2045302304 @default.
• W2056542903 cites W2057704439 @default.
• W2056542903 cites W2104472885 @default.
• W2056542903 cites W2132235135 @default.
• W2056542903 cites W2141378441 @default.
• W2056542903 cites W2141863606 @default.
• W2056542903 cites W2169046402 @default.
• W2056542903 doi "https://doi.org/10.1021/ma048605t" @default.
• W2056542903 hasPublicationYear "2004" @default.
• W2056542903 type Work @default.
• W2056542903 sameAs 2056542903 @default.
• W2056542903 citedByCount "61" @default.
• W2056542903 countsByYear W20565429032012 @default.
• W2056542903 countsByYear W20565429032013 @default.
• W2056542903 countsByYear W20565429032014 @default.
• W2056542903 countsByYear W20565429032015 @default.
• W2056542903 countsByYear W20565429032016 @default.
• W2056542903 countsByYear W20565429032017 @default.
• W2056542903 countsByYear W20565429032018 @default.
• W2056542903 countsByYear W20565429032019 @default.
• W2056542903 countsByYear W20565429032021 @default.
• W2056542903 crossrefType "journal-article" @default.
• W2056542903 hasAuthorship W2056542903A5069932768 @default.
• W2056542903 hasAuthorship W2056542903A5086283473 @default.
• W2056542903 hasConcept C10390740 @default.
• W2056542903 hasConcept C112613896 @default.
• W2056542903 hasConcept C112887158 @default.
• W2056542903 hasConcept C121332964 @default.
• W2056542903 hasConcept C12554922 @default.
• W2056542903 hasConcept C133495861 @default.
• W2056542903 hasConcept C137277065 @default.
• W2056542903 hasConcept C178790620 @default.
• W2056542903 hasConcept C180577832 @default.
• W2056542903 hasConcept C185592680 @default.
• W2056542903 hasConcept C2777339483 @default.
• W2056542903 hasConcept C2779262620 @default.
• W2056542903 hasConcept C29688787 @default.
• W2056542903 hasConcept C32909587 @default.
• W2056542903 hasConcept C43617362 @default.
• W2056542903 hasConcept C49853544 @default.
• W2056542903 hasConcept C519063684 @default.
• W2056542903 hasConcept C521977710 @default.
• W2056542903 hasConcept C55493867 @default.
• W2056542903 hasConcept C62520636 @default.
• W2056542903 hasConcept C71240020 @default.
• W2056542903 hasConcept C86803240 @default.
• W2056542903 hasConcept C91881484 @default.
• W2056542903 hasConceptScore W2056542903C10390740 @default.
• W2056542903 hasConceptScore W2056542903C112613896 @default.
• W2056542903 hasConceptScore W2056542903C112887158 @default.
• W2056542903 hasConceptScore W2056542903C121332964 @default.
• W2056542903 hasConceptScore W2056542903C12554922 @default.
• W2056542903 hasConceptScore W2056542903C133495861 @default.
• W2056542903 hasConceptScore W2056542903C137277065 @default.
• W2056542903 hasConceptScore W2056542903C178790620 @default.
• W2056542903 hasConceptScore W2056542903C180577832 @default.
• W2056542903 hasConceptScore W2056542903C185592680 @default.
• W2056542903 hasConceptScore W2056542903C2777339483 @default.
• W2056542903 hasConceptScore W2056542903C2779262620 @default.
• W2056542903 hasConceptScore W2056542903C29688787 @default.
• W2056542903 hasConceptScore W2056542903C32909587 @default.
• W2056542903 hasConceptScore W2056542903C43617362 @default.
• W2056542903 hasConceptScore W2056542903C49853544 @default.
• W2056542903 hasConceptScore W2056542903C519063684 @default.
• W2056542903 hasConceptScore W2056542903C521977710 @default.
• W2056542903 hasConceptScore W2056542903C55493867 @default.
• W2056542903 hasConceptScore W2056542903C62520636 @default.
• W2056542903 hasConceptScore W2056542903C71240020 @default.
• W2056542903 hasConceptScore W2056542903C86803240 @default.
• W2056542903 hasConceptScore W2056542903C91881484 @default.
• W2056542903 hasIssue "24" @default.
• W2056542903 hasLocation W20565429031 @default.
• W2056542903 hasOpenAccess W2056542903 @default.
• W2056542903 hasPrimaryLocation W20565429031 @default.
• W2056542903 hasRelatedWork W1729575672 @default.
• W2056542903 hasRelatedWork W194832506 @default.
• W2056542903 hasRelatedWork W1987156454 @default.
• W2056542903 hasRelatedWork W2029048755 @default.
• W2056542903 hasRelatedWork W2049818938 @default.
• W2056542903 hasRelatedWork W2059950795 @default.
• W2056542903 hasRelatedWork W2354273652 @default.
• W2056542903 hasRelatedWork W2362139150 @default.
• W2056542903 hasRelatedWork W29407805 @default.
• W2056542903 hasRelatedWork W332794955 @default.

• next