Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056544326> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2056544326 endingPage "409" @default.
- W2056544326 startingPage "383" @default.
- W2056544326 abstract "It has been shown that injection of lipopolysaccharides, derived from a variety of Gram-negative bacterial species, evokes in mice a rapidly developing rise in resistance to infection with Gram-negative pathogens. This is accompanied by an elevation in properdin titer, at times to levels 2 to 3 times the normal. The rate, magnitude, and duration of these responses are dependent on many factors, the most important of which are the quantity and timing of the lipopolysaccharide administered. The increased resistance to infection evoked in mice by lipopolysaccharides was effective against infections produced by endotoxin-bearing organisms-bacterial species highly susceptible in vitro to the bactericidal action of the properdin system. Properdin titers of mice prior to infection provide an incomplete picture of the subsequent reaction of the host to the infective agent. Following infection with Gram-negative organisms, properdin levels accurately reflect the bacteriologic course and outcome of the infection. Thus, in control animals, properdin titers progressively declined and the animals died, while in mice appropriately treated with lipopolysaccharide, properdin levels were either maintained in the normal range or increased, depending on the dose and time of administration of lipopolysaccharide; this was always accompanied by successful management of the infection. The complex nature of the alterations produced in the host by lipopolysaccharides is stressed. It is pointed out that the increase in the ability of the host to cope with Gram-negative infections may be the result of stimulation of other defense mechanisms, in addition to the properdin system." @default.
- W2056544326 created "2016-06-24" @default.
- W2056544326 creator A5011055218 @default.
- W2056544326 creator A5038513794 @default.
- W2056544326 date "1956-09-01" @default.
- W2056544326 modified "2023-09-26" @default.
- W2056544326 title "INCREASED RESISTANCE TO INFECTION AND ACCOMPANYING ALTERATION IN PROPERDIN LEVELS FOLLOWING ADMINISTRATION OF BACTERIAL LIPOPOLYSACCHARIDES" @default.
- W2056544326 cites W1501115740 @default.
- W2056544326 cites W1526683754 @default.
- W2056544326 cites W1610691705 @default.
- W2056544326 cites W1966944472 @default.
- W2056544326 cites W1975908451 @default.
- W2056544326 cites W1984423531 @default.
- W2056544326 cites W1993683022 @default.
- W2056544326 cites W1998453159 @default.
- W2056544326 cites W2033500725 @default.
- W2056544326 cites W2045377811 @default.
- W2056544326 cites W2080459981 @default.
- W2056544326 cites W2085558892 @default.
- W2056544326 cites W2135612270 @default.
- W2056544326 cites W2197918586 @default.
- W2056544326 cites W2317575941 @default.
- W2056544326 cites W2337380454 @default.
- W2056544326 cites W2401110814 @default.
- W2056544326 cites W96747349 @default.
- W2056544326 doi "https://doi.org/10.1084/jem.104.3.383" @default.
- W2056544326 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2136568" @default.
- W2056544326 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13357692" @default.
- W2056544326 hasPublicationYear "1956" @default.
- W2056544326 type Work @default.
- W2056544326 sameAs 2056544326 @default.
- W2056544326 citedByCount "154" @default.
- W2056544326 countsByYear W20565443262017 @default.
- W2056544326 countsByYear W20565443262018 @default.
- W2056544326 countsByYear W20565443262019 @default.
- W2056544326 countsByYear W20565443262020 @default.
- W2056544326 countsByYear W20565443262021 @default.
- W2056544326 countsByYear W20565443262022 @default.
- W2056544326 crossrefType "journal-article" @default.
- W2056544326 hasAuthorship W2056544326A5011055218 @default.
- W2056544326 hasAuthorship W2056544326A5038513794 @default.
- W2056544326 hasBestOaLocation W20565443261 @default.
- W2056544326 hasConcept C104317684 @default.
- W2056544326 hasConcept C111684460 @default.
- W2056544326 hasConcept C134018914 @default.
- W2056544326 hasConcept C159654299 @default.
- W2056544326 hasConcept C203014093 @default.
- W2056544326 hasConcept C24998067 @default.
- W2056544326 hasConcept C2776051709 @default.
- W2056544326 hasConcept C2778754761 @default.
- W2056544326 hasConcept C2779341262 @default.
- W2056544326 hasConcept C32611913 @default.
- W2056544326 hasConcept C547475151 @default.
- W2056544326 hasConcept C55493867 @default.
- W2056544326 hasConcept C7407320 @default.
- W2056544326 hasConcept C86803240 @default.
- W2056544326 hasConcept C8891405 @default.
- W2056544326 hasConcept C89423630 @default.
- W2056544326 hasConceptScore W2056544326C104317684 @default.
- W2056544326 hasConceptScore W2056544326C111684460 @default.
- W2056544326 hasConceptScore W2056544326C134018914 @default.
- W2056544326 hasConceptScore W2056544326C159654299 @default.
- W2056544326 hasConceptScore W2056544326C203014093 @default.
- W2056544326 hasConceptScore W2056544326C24998067 @default.
- W2056544326 hasConceptScore W2056544326C2776051709 @default.
- W2056544326 hasConceptScore W2056544326C2778754761 @default.
- W2056544326 hasConceptScore W2056544326C2779341262 @default.
- W2056544326 hasConceptScore W2056544326C32611913 @default.
- W2056544326 hasConceptScore W2056544326C547475151 @default.
- W2056544326 hasConceptScore W2056544326C55493867 @default.
- W2056544326 hasConceptScore W2056544326C7407320 @default.
- W2056544326 hasConceptScore W2056544326C86803240 @default.
- W2056544326 hasConceptScore W2056544326C8891405 @default.
- W2056544326 hasConceptScore W2056544326C89423630 @default.
- W2056544326 hasIssue "3" @default.
- W2056544326 hasLocation W20565443261 @default.
- W2056544326 hasLocation W20565443262 @default.
- W2056544326 hasLocation W20565443263 @default.
- W2056544326 hasLocation W20565443264 @default.
- W2056544326 hasOpenAccess W2056544326 @default.
- W2056544326 hasPrimaryLocation W20565443261 @default.
- W2056544326 hasRelatedWork W2035492084 @default.
- W2056544326 hasRelatedWork W2043455657 @default.
- W2056544326 hasRelatedWork W2056544326 @default.
- W2056544326 hasRelatedWork W2057948995 @default.
- W2056544326 hasRelatedWork W2139073594 @default.
- W2056544326 hasRelatedWork W3017822181 @default.
- W2056544326 hasRelatedWork W3032210197 @default.
- W2056544326 hasRelatedWork W4283821855 @default.
- W2056544326 hasRelatedWork W4381570565 @default.
- W2056544326 hasRelatedWork W573847062 @default.
- W2056544326 hasVolume "104" @default.
- W2056544326 isParatext "false" @default.
- W2056544326 isRetracted "false" @default.
- W2056544326 magId "2056544326" @default.
- W2056544326 workType "article" @default.