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• W2056547682 abstract "Autoimmunity can be viewed as the price we pay in order to have a highly diverse TCR repertoire. This is not to say that every effort isn't made by the immune system to prevent autoimmune disease. During thymic development, and later in the periphery, the TCR repertoire is continuously purged of cells that are activated by self-antigens. Other lymphocytes are recruited to join a legion of T regulatory cells that assist in preventing ‘friendly fire’. Recent studies continue to reveal the importance of the composition of the T cell repertoire in predisposing an individual to autoimmune disease." @default.
• W2056547682 created "2016-06-24" @default.
• W2056547682 creator A5014469526 @default.
• W2056547682 creator A5046916138 @default.
• W2056547682 date "2001-12-01" @default.
• W2056547682 modified "2023-10-11" @default.
• W2056547682 title "The T-cell repertoire available for recognition of self-antigens" @default.
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• W2056547682 doi "https://doi.org/10.1016/s0952-7915(01)00272-2" @default.
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