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- W2056551657 abstract "Effects of repeated daily intracerebroventricular injections of 1 microg of glucagon-like peptide-1 (7-36) amide (tGLP-1) on feeding and drinking behaviour, as well as neurohypophysial hormone secretion, was investigated in rats drinking tap water or 2% saline for 6 days. In euhydrated rats, tGLP-1 decreased moderately food and water consumption without a marked reduction of body weight. In salt-loaded rats, tGLP-1 considerably inhibited saline intake. On the other hand, food consumption and body weight changes were similar in vehicle- and tGLP-1-treated rats drinking 2% saline. Osmotic stimulation resulted in the augmented release of both neurohypophysial hormones. tGLP-1 did not alter plasma vasopressin and oxytocin concentrations either in euhydrated or osmotically stimulated rats. It is concluded that tGLP-1 may modify feeding and drinking behaviour under conditions of normal or disturbed water-electrolyte balance in the rat." @default.
- W2056551657 created "2016-06-24" @default.
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- W2056551657 date "2003-01-01" @default.
- W2056551657 modified "2023-09-23" @default.
- W2056551657 title "Effects of tGLP-1 on feeding behaviour and neurohypophysial function under chronic osmotic stimulation" @default.
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- W2056551657 doi "https://doi.org/10.1016/s0031-9384(02)00891-0" @default.
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