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- W2056556444 abstract "The role of antibodies in the pathogenesis of chronic rejection is increasingly acknowledged. In contrast, whether B-cell clusters, which have been recently identified in chronically rejected allografts, actively participate in the process or are only an epiphenomenon remain a matter of debate. Integrating recently published data, we put forward explanations that reconcile the conflicting conclusions of experimental and biopsy-based studies. Finally, we propose a unified model in which B-cell clusters as part of intragraft tertiary lymphoid tissue can play deleterious or regulatory roles and therefore actively modulate the kinetics of chronic rejection." @default.
- W2056556444 created "2016-06-24" @default.
- W2056556444 creator A5066933536 @default.
- W2056556444 date "2011-07-27" @default.
- W2056556444 modified "2023-10-16" @default.
- W2056556444 title "Pathophysiologic Significance of B-Cell Clusters in Chronically Rejected Grafts" @default.
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- W2056556444 doi "https://doi.org/10.1097/tp.0b013e31821f74fe" @default.
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