FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056562907> ?p ?o ?g. }

• W2056562907 endingPage "250" @default.
• W2056562907 startingPage "245" @default.
• W2056562907 abstract "The lyophilized aqueous extracts from Cistus incanus L. (CI) and Cistus monspeliensis L. (CM) collected in Sicily were studied in order to evaluate their myorelaxant activity by using isolated smooth muscle of rat ileum and rat aorta. Both CI and CM extracts concentration-dependently inhibited the contractile response to acetylcholine (ACh), phenylephrine (PE) and to 100 mM KCl. The concentration-contraction curves to ACh in ileum and to PE in aorta, were displaced to the right by Cistus extracts in a non-competitive manner, with a depression of the maximum contractile response. The EC50 (microg/ml) of CM and CI were: ileum/KCl, CM 457+/-99, CI 681+/-80; ileum/ACh 100 microM, CM 297+/-66, CI 335+/-41; aorta/KCl, CM 360+/-21, CI 843+/-36; and aorta/PE 10 microM, CM 287+/-33, CI 451+/-58. The two extracts resulted almost equi-active in ileum, whereas CM was more active than CI in aorta. These data indicate that Cistus extracts act as spasmolytic on intestinal and vascular smooth muscle. The antagonism they exert on ACh-, PE- and KCl-evoked contractions seems to be functional, because it is not specifically directed toward any particular receptor; furthermore, a calcium-antagonist activity seems unlikely, since the extracts are capable of completely block the contractile response to agonists." @default.
• W2056562907 created "2016-06-24" @default.
• W2056562907 creator A5008736864 @default.
• W2056562907 creator A5034467556 @default.
• W2056562907 creator A5046166083 @default.
• W2056562907 creator A5056670940 @default.
• W2056562907 creator A5077442076 @default.
• W2056562907 creator A5083678641 @default.
• W2056562907 date "2004-06-01" @default.
• W2056562907 modified "2023-09-27" @default.
• W2056562907 title "Cistus incanus and Cistus monspeliensis inhibit the contractile response in isolated rat smooth muscle" @default.
• W2056562907 cites W1583152320 @default.
• W2056562907 cites W1966432961 @default.
• W2056562907 cites W1968511210 @default.
• W2056562907 cites W1974735376 @default.
• W2056562907 cites W1975320072 @default.
• W2056562907 cites W1982403830 @default.
• W2056562907 cites W1985120853 @default.
• W2056562907 cites W1987903467 @default.
• W2056562907 cites W2003454945 @default.
• W2056562907 cites W2003497264 @default.
• W2056562907 cites W2005394877 @default.
• W2056562907 cites W2010792523 @default.
• W2056562907 cites W2012716588 @default.
• W2056562907 cites W2014219309 @default.
• W2056562907 cites W2021314891 @default.
• W2056562907 cites W2024444842 @default.
• W2056562907 cites W2034070305 @default.
• W2056562907 cites W2041862222 @default.
• W2056562907 cites W2046885170 @default.
• W2056562907 cites W2053748313 @default.
• W2056562907 cites W2056087617 @default.
• W2056562907 cites W2075013148 @default.
• W2056562907 cites W2076138751 @default.
• W2056562907 cites W2076550642 @default.
• W2056562907 cites W2164541169 @default.
• W2056562907 cites W2165992926 @default.
• W2056562907 cites W2177428085 @default.
• W2056562907 doi "https://doi.org/10.1016/j.jep.2004.02.020" @default.
• W2056562907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15138007" @default.
• W2056562907 hasPublicationYear "2004" @default.
• W2056562907 type Work @default.
• W2056562907 sameAs 2056562907 @default.
• W2056562907 citedByCount "19" @default.
• W2056562907 countsByYear W20565629072012 @default.
• W2056562907 countsByYear W20565629072013 @default.
• W2056562907 countsByYear W20565629072014 @default.
• W2056562907 countsByYear W20565629072017 @default.
• W2056562907 countsByYear W20565629072020 @default.
• W2056562907 countsByYear W20565629072021 @default.
• W2056562907 countsByYear W20565629072023 @default.
• W2056562907 crossrefType "journal-article" @default.
• W2056562907 hasAuthorship W2056562907A5008736864 @default.
• W2056562907 hasAuthorship W2056562907A5034467556 @default.
• W2056562907 hasAuthorship W2056562907A5046166083 @default.
• W2056562907 hasAuthorship W2056562907A5056670940 @default.
• W2056562907 hasAuthorship W2056562907A5077442076 @default.
• W2056562907 hasAuthorship W2056562907A5083678641 @default.
• W2056562907 hasConcept C126322002 @default.
• W2056562907 hasConcept C134018914 @default.
• W2056562907 hasConcept C163415756 @default.
• W2056562907 hasConcept C170493617 @default.
• W2056562907 hasConcept C185592680 @default.
• W2056562907 hasConcept C2775910092 @default.
• W2056562907 hasConcept C2776050358 @default.
• W2056562907 hasConcept C2777226302 @default.
• W2056562907 hasConcept C2777383412 @default.
• W2056562907 hasConcept C2777952589 @default.
• W2056562907 hasConcept C2779961880 @default.
• W2056562907 hasConcept C2779980429 @default.
• W2056562907 hasConcept C71924100 @default.
• W2056562907 hasConcept C84393581 @default.
• W2056562907 hasConcept C86803240 @default.
• W2056562907 hasConcept C98274493 @default.
• W2056562907 hasConceptScore W2056562907C126322002 @default.
• W2056562907 hasConceptScore W2056562907C134018914 @default.
• W2056562907 hasConceptScore W2056562907C163415756 @default.
• W2056562907 hasConceptScore W2056562907C170493617 @default.
• W2056562907 hasConceptScore W2056562907C185592680 @default.
• W2056562907 hasConceptScore W2056562907C2775910092 @default.
• W2056562907 hasConceptScore W2056562907C2776050358 @default.
• W2056562907 hasConceptScore W2056562907C2777226302 @default.
• W2056562907 hasConceptScore W2056562907C2777383412 @default.
• W2056562907 hasConceptScore W2056562907C2777952589 @default.
• W2056562907 hasConceptScore W2056562907C2779961880 @default.
• W2056562907 hasConceptScore W2056562907C2779980429 @default.
• W2056562907 hasConceptScore W2056562907C71924100 @default.
• W2056562907 hasConceptScore W2056562907C84393581 @default.
• W2056562907 hasConceptScore W2056562907C86803240 @default.
• W2056562907 hasConceptScore W2056562907C98274493 @default.
• W2056562907 hasIssue "2-3" @default.
• W2056562907 hasLocation W20565629071 @default.
• W2056562907 hasLocation W20565629072 @default.
• W2056562907 hasOpenAccess W2056562907 @default.
• W2056562907 hasPrimaryLocation W20565629071 @default.
• W2056562907 hasRelatedWork W1963843006 @default.
• W2056562907 hasRelatedWork W2042527256 @default.
• W2056562907 hasRelatedWork W2094046008 @default.

• next