Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056566680> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2056566680 endingPage "635" @default.
- W2056566680 startingPage "632" @default.
- W2056566680 abstract "The effects of four retinoids, all-trans-retinoic acid (RA), 13-cis-retinoic acid (13-cis-RA), aromatic retinoid, and arotinoid ethyl ester ( arotinoid ) were examined on the skin of the rhino mouse. Rhino mouse skin is characterized by the presence of keratin-containing utricles attached to the epidermis, and subcutaneous cysts, both of which are derived from hair follicles. The utricles were examined in horizontal sheets of epidermis, and in vertical histologic sections. After applications of 0.1 ml of 0.1% RA, 0.1% 13-cis-RA, 0.1% aromatic retinoid, or 0.001% arotinoid in acetone to the dorsal skin for 5 days a week for 2 weeks, there was a reduction of utricle diameter to 45%, 52%, 30%, and 31% of acetone-treated controls, respectively. Histologic examination of the epidermis revealed that a dose-dependent hyperplasia and thickening of the epidermis and the stratum granulosum was induced by the retinoids when given at subtoxic doses, being most marked after arotinoid or RA. The thickness of the walls of the utricles also increased with increasing dose of retinoid, paralleling the changes in the epidermis. After doses of 0.1% RA and 0.001% arotinoid , the utricles resembled the hair follicles of hairless mice. Hyperplasia of the epidermis appears to be a primary effect of retinoids or rhino mouse skin. Hyperproliferation of the utricle wall is accompanied by a reduction in the size of the utricle lumen, preceding eventual differentiation of the utricles to normal-looking pilar units." @default.
- W2056566680 created "2016-06-24" @default.
- W2056566680 creator A5017687789 @default.
- W2056566680 creator A5060061626 @default.
- W2056566680 creator A5072890715 @default.
- W2056566680 date "1984-06-01" @default.
- W2056566680 modified "2023-10-01" @default.
- W2056566680 title "Histologic Changes in the Skin of the Rhino Mouse (hrrhhrrh) Induced by Retinoids" @default.
- W2056566680 cites W1536413306 @default.
- W2056566680 cites W2066084493 @default.
- W2056566680 cites W2081526174 @default.
- W2056566680 cites W2094029304 @default.
- W2056566680 cites W2096677772 @default.
- W2056566680 cites W2101794341 @default.
- W2056566680 doi "https://doi.org/10.1111/1523-1747.ep12261472" @default.
- W2056566680 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6586859" @default.
- W2056566680 hasPublicationYear "1984" @default.
- W2056566680 type Work @default.
- W2056566680 sameAs 2056566680 @default.
- W2056566680 citedByCount "64" @default.
- W2056566680 countsByYear W20565666802013 @default.
- W2056566680 countsByYear W20565666802014 @default.
- W2056566680 countsByYear W20565666802015 @default.
- W2056566680 countsByYear W20565666802016 @default.
- W2056566680 countsByYear W20565666802017 @default.
- W2056566680 countsByYear W20565666802019 @default.
- W2056566680 countsByYear W20565666802021 @default.
- W2056566680 countsByYear W20565666802023 @default.
- W2056566680 crossrefType "journal-article" @default.
- W2056566680 hasAuthorship W2056566680A5017687789 @default.
- W2056566680 hasAuthorship W2056566680A5060061626 @default.
- W2056566680 hasAuthorship W2056566680A5072890715 @default.
- W2056566680 hasBestOaLocation W20565666801 @default.
- W2056566680 hasConcept C104317684 @default.
- W2056566680 hasConcept C105702510 @default.
- W2056566680 hasConcept C126322002 @default.
- W2056566680 hasConcept C134018914 @default.
- W2056566680 hasConcept C151730666 @default.
- W2056566680 hasConcept C185592680 @default.
- W2056566680 hasConcept C2775954498 @default.
- W2056566680 hasConcept C2776458125 @default.
- W2056566680 hasConcept C2777562237 @default.
- W2056566680 hasConcept C2779156968 @default.
- W2056566680 hasConcept C2781121885 @default.
- W2056566680 hasConcept C55493867 @default.
- W2056566680 hasConcept C71924100 @default.
- W2056566680 hasConcept C81241287 @default.
- W2056566680 hasConcept C86803240 @default.
- W2056566680 hasConceptScore W2056566680C104317684 @default.
- W2056566680 hasConceptScore W2056566680C105702510 @default.
- W2056566680 hasConceptScore W2056566680C126322002 @default.
- W2056566680 hasConceptScore W2056566680C134018914 @default.
- W2056566680 hasConceptScore W2056566680C151730666 @default.
- W2056566680 hasConceptScore W2056566680C185592680 @default.
- W2056566680 hasConceptScore W2056566680C2775954498 @default.
- W2056566680 hasConceptScore W2056566680C2776458125 @default.
- W2056566680 hasConceptScore W2056566680C2777562237 @default.
- W2056566680 hasConceptScore W2056566680C2779156968 @default.
- W2056566680 hasConceptScore W2056566680C2781121885 @default.
- W2056566680 hasConceptScore W2056566680C55493867 @default.
- W2056566680 hasConceptScore W2056566680C71924100 @default.
- W2056566680 hasConceptScore W2056566680C81241287 @default.
- W2056566680 hasConceptScore W2056566680C86803240 @default.
- W2056566680 hasIssue "6" @default.
- W2056566680 hasLocation W20565666801 @default.
- W2056566680 hasLocation W20565666802 @default.
- W2056566680 hasOpenAccess W2056566680 @default.
- W2056566680 hasPrimaryLocation W20565666801 @default.
- W2056566680 hasRelatedWork W2007096036 @default.
- W2056566680 hasRelatedWork W2007118908 @default.
- W2056566680 hasRelatedWork W2012560559 @default.
- W2056566680 hasRelatedWork W2055895939 @default.
- W2056566680 hasRelatedWork W2069023992 @default.
- W2056566680 hasRelatedWork W2072976644 @default.
- W2056566680 hasRelatedWork W2094990782 @default.
- W2056566680 hasRelatedWork W2150724508 @default.
- W2056566680 hasRelatedWork W2527739724 @default.
- W2056566680 hasRelatedWork W4322495910 @default.
- W2056566680 hasVolume "82" @default.
- W2056566680 isParatext "false" @default.
- W2056566680 isRetracted "false" @default.
- W2056566680 magId "2056566680" @default.
- W2056566680 workType "article" @default.