Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056571449> ?p ?o ?g. }
- W2056571449 endingPage "3452" @default.
- W2056571449 startingPage "3442" @default.
- W2056571449 abstract "Unilateral damage to cortical areas in the frontal cortex produces sensorimotor deficits on the side contralateral to the lesion. Although there are anecdotal reports of bilateral deficits after stroke in humans and in experimental animals, little is known of the effects of unilateral lesions on the same side of the body. The objective of the present study was to make a systematic examination of the motor skills of the ipsilateral forelimb after frontal cortex lesions to either the motor cortex by devascularization of the surface blood vessels (pial stroke), or to the lateral cortex by electrocoagulation of the distal branches of the middle cerebral artery (MCA stroke). Plastic processes in the intact hemisphere were documented using Golgi-Cox dendritic analysis and by intracortical microstimulation analysis. Although tests of reflexive responses in forelimb placing identified a contralateral motor impairment following both cortical lesions, quantitative and qualitative measures of skilled reaching identified a severe ipsilateral impairment from which recovery was substantial but incomplete. Golgi-impregnated pyramidal cells in the forelimb area showed an increase in dendritic length and branching. Electrophysiological mapping showed normal size forelimb representations in the lesioned rats relative to control animals. The finding of an enduring ipsilateral impairment in skilled movement is consistent with a large but more anecdotal literature in rats, nonhuman primates and humans, and suggests that plastic changes in the intact hemisphere are related to that hemisphere's contribution to skilled movement." @default.
- W2056571449 created "2016-06-24" @default.
- W2056571449 creator A5002246735 @default.
- W2056571449 creator A5022434691 @default.
- W2056571449 creator A5029840683 @default.
- W2056571449 creator A5035495513 @default.
- W2056571449 creator A5055291900 @default.
- W2056571449 creator A5059503273 @default.
- W2056571449 date "2004-12-01" @default.
- W2056571449 modified "2023-10-14" @default.
- W2056571449 title "Evidence for bilateral control of skilled movements: ipsilateral skilled forelimb reaching deficits and functional recovery in rats follow motor cortex and lateral frontal cortex lesions" @default.
- W2056571449 cites W111104 @default.
- W2056571449 cites W1696376591 @default.
- W2056571449 cites W1781000532 @default.
- W2056571449 cites W1807367985 @default.
- W2056571449 cites W1901269612 @default.
- W2056571449 cites W1920845131 @default.
- W2056571449 cites W1966702161 @default.
- W2056571449 cites W1974245606 @default.
- W2056571449 cites W1975327189 @default.
- W2056571449 cites W1977619632 @default.
- W2056571449 cites W1979802782 @default.
- W2056571449 cites W1981171404 @default.
- W2056571449 cites W1984857190 @default.
- W2056571449 cites W1988413123 @default.
- W2056571449 cites W1993043544 @default.
- W2056571449 cites W1993829102 @default.
- W2056571449 cites W1996020467 @default.
- W2056571449 cites W1996528036 @default.
- W2056571449 cites W1999816939 @default.
- W2056571449 cites W2000604528 @default.
- W2056571449 cites W2002850293 @default.
- W2056571449 cites W2003414509 @default.
- W2056571449 cites W2004476854 @default.
- W2056571449 cites W2006490984 @default.
- W2056571449 cites W2012564965 @default.
- W2056571449 cites W2015423598 @default.
- W2056571449 cites W2017078856 @default.
- W2056571449 cites W2019273642 @default.
- W2056571449 cites W2020683010 @default.
- W2056571449 cites W2023760861 @default.
- W2056571449 cites W2028496416 @default.
- W2056571449 cites W2031776605 @default.
- W2056571449 cites W2033216968 @default.
- W2056571449 cites W2035412143 @default.
- W2056571449 cites W2035471834 @default.
- W2056571449 cites W2037390002 @default.
- W2056571449 cites W2037880715 @default.
- W2056571449 cites W2038636807 @default.
- W2056571449 cites W2039680888 @default.
- W2056571449 cites W2049319646 @default.
- W2056571449 cites W2049836559 @default.
- W2056571449 cites W2051333567 @default.
- W2056571449 cites W2054631871 @default.
- W2056571449 cites W2058164375 @default.
- W2056571449 cites W2059407399 @default.
- W2056571449 cites W2064468938 @default.
- W2056571449 cites W2064507242 @default.
- W2056571449 cites W2065584262 @default.
- W2056571449 cites W2065723600 @default.
- W2056571449 cites W2067281910 @default.
- W2056571449 cites W2067317555 @default.
- W2056571449 cites W2072795377 @default.
- W2056571449 cites W2076324726 @default.
- W2056571449 cites W2077094621 @default.
- W2056571449 cites W2078089259 @default.
- W2056571449 cites W2081740279 @default.
- W2056571449 cites W2087497042 @default.
- W2056571449 cites W2088092025 @default.
- W2056571449 cites W2089136890 @default.
- W2056571449 cites W2093203706 @default.
- W2056571449 cites W2093736276 @default.
- W2056571449 cites W2094308504 @default.
- W2056571449 cites W2095251270 @default.
- W2056571449 cites W2103888564 @default.
- W2056571449 cites W2115484107 @default.
- W2056571449 cites W2120616138 @default.
- W2056571449 cites W2123068902 @default.
- W2056571449 cites W2127838758 @default.
- W2056571449 cites W2129658890 @default.
- W2056571449 cites W2131628166 @default.
- W2056571449 cites W2140626683 @default.
- W2056571449 cites W2141161195 @default.
- W2056571449 cites W2141711957 @default.
- W2056571449 cites W2146672919 @default.
- W2056571449 cites W2153195574 @default.
- W2056571449 cites W2166496419 @default.
- W2056571449 cites W2166914876 @default.
- W2056571449 cites W2167516646 @default.
- W2056571449 cites W2168796299 @default.
- W2056571449 cites W2172042520 @default.
- W2056571449 cites W2279676565 @default.
- W2056571449 cites W2334275515 @default.
- W2056571449 cites W2397670392 @default.
- W2056571449 cites W2742628764 @default.
- W2056571449 cites W41829633 @default.
- W2056571449 cites W4242459955 @default.
- W2056571449 cites W4251124342 @default.