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- W2056572339 abstract "Rebound insomnia followed the withdrawal of three benzodiazepine hypnotic drugs, each of which had been administered in a single nightly dose for only short-term periods. The intense worsening of sleep is attributed to the short duration of the action of these drugs. A hypothesis involving benzodiazepine receptors in the brain is proposed in which there is a delay or lag in replacement of endogenous benzodiazepine-like molecules after the abrupt withdrawal of exogenous drugs." @default.
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- W2056572339 date "1978-09-15" @default.
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- W2056572339 title "Rebound Insomnia: A New Clinical Syndrome" @default.
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- W2056572339 doi "https://doi.org/10.1126/science.684426" @default.
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