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• W2056574413 abstract "Studies have been carried out to determine the effect of bacterial infection on CSF production, CFU-C activation, and bacterial clearance by mature granulocytes in mice infected with Escherichia coli. These studies have shown that immediately after bacterial infection (5 minutes), serum colony-stimulating factor (CSF) levels and bone marrow colony-forming units in culture (CFU-C) levels are elevated. This is followed by oscillator rises in both of these parameters and the appearance of granulocytes in the infected site. With clearance of bacteria, CSF and CFU-C levels return to normal. These studies have indicated further that bacterial infection is a major stimulus for granulocyte production through the CSF-CFU-C system and that clearance of bacteria by mature granulocytes may serve as a negative feedback regulatory arm." @default.
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• W2056574413 date "1981-10-01" @default.
• W2056574413 modified "2023-09-23" @default.
• W2056574413 title "Regulation of granulopoiesis and distribution of granulocytes in early phase of bacterial infection" @default.
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• W2056574413 doi "https://doi.org/10.1002/jcp.1041090103" @default.
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