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- W2056574616 abstract "Type 2 diabetes is the most common form of diabetes, accounting for over 90% of cases. Current treatment approaches for type 2 diabetes include diet, exercise, and a variety of pharmacologic agents, including insulin, biguanides, sulfonylureas, and thiazolidinediones.In the present scenario, researchers focused themselves on thiazolidine ring-based compounds to cure type 2 diabetes mellitus. Among the peroxisome proliferator activated receptor (PPAR) family, PPAR-γ is the most effective in curing glucose homeostasis.Thiazolidine ring-based compounds act as PPAR-γ agonists, and herein, we have successfully developed nine derivatives of thiazolidine ring-based compounds that are found to be biologically potent using two-dimensional quantitative structure-activity relationship model." @default.
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- W2056574616 date "2013-01-01" @default.
- W2056574616 modified "2023-09-25" @default.
- W2056574616 title "Quantitative structure-activity relationship analysis of thiazolidineones: potent antidiabetic compounds" @default.
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- W2056574616 doi "https://doi.org/10.1515/dmdi-2012-0036" @default.
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