FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056575247> ?p ?o ?g. }

• W2056575247 endingPage "14" @default.
• W2056575247 startingPage "8" @default.
• W2056575247 abstract "Pancreatic adenocarcinoma causes diabetes mellitus by releasing factors interfering with glucose metabolism.We verified in isolated rat hepatocytes the molecular weight (MW) of the fraction from pancreatic cancer cell conditioned media (CM) that altered glucose metabolism and ascertained, using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis, whether there is any common peptide in CM and in the sera of patients with pancreatic cancer.Sera was obtained from patients with pancreatic cancer ( n = 14) and chronic pancreatitis ( n = 9) and healthy control subjects ( n = 10). Conditioned medium (CM) was obtained from the following cell lines: MIA PaCa 2, PSK-1, PANC-1, and CAPAN-1. Two fractions (MW of less than 30,000 Da and less than 10,000 Da) were obtained from patients' sera, from CM, and from non-CM (NCM) after two-step ultrafiltration. Rat hepatocytes were incubated with CM and NCM. The peptide profile of patients' sera, CM, and NCM were analyzed using MALDI-MS.In rat hepatocytes, glucose metabolism was impaired by CM from all the pancreatic cancer cell lines and by CM with an MW of less than 10,000 Da. Two peptides (m/z 2030 and 2726) were found in CM and patients' sera. Only the peptide at m/z 2030 was found to be associated with the presence of diabetes.A peptide at m/z 2030 may be a putative pancreatic cancer-associated diabetogenic factor." @default.
• W2056575247 created "2016-06-24" @default.
• W2056575247 creator A5001558382 @default.
• W2056575247 creator A5018059398 @default.
• W2056575247 creator A5031869445 @default.
• W2056575247 creator A5037249662 @default.
• W2056575247 creator A5050450297 @default.
• W2056575247 creator A5051237706 @default.
• W2056575247 creator A5060268889 @default.
• W2056575247 creator A5063101360 @default.
• W2056575247 creator A5071801847 @default.
• W2056575247 creator A5082322650 @default.
• W2056575247 creator A5091598147 @default.
• W2056575247 date "2002-01-01" @default.
• W2056575247 modified "2023-10-18" @default.
• W2056575247 title "Putative Pancreatic Cancer-Associated Diabetogenic Factor: 2030 MW Peptide" @default.
• W2056575247 cites W1608045086 @default.
• W2056575247 cites W1966429815 @default.
• W2056575247 cites W1974302575 @default.
• W2056575247 cites W1976441932 @default.
• W2056575247 cites W2008030640 @default.
• W2056575247 cites W2008260305 @default.
• W2056575247 cites W2009331852 @default.
• W2056575247 cites W2023763925 @default.
• W2056575247 cites W2030449116 @default.
• W2056575247 cites W2035700643 @default.
• W2056575247 cites W2045901590 @default.
• W2056575247 cites W2054574371 @default.
• W2056575247 cites W2058446582 @default.
• W2056575247 cites W2060012995 @default.
• W2056575247 cites W2062999949 @default.
• W2056575247 cites W2088231412 @default.
• W2056575247 cites W2120489033 @default.
• W2056575247 cites W2325477988 @default.
• W2056575247 cites W4251596994 @default.
• W2056575247 cites W4252590854 @default.
• W2056575247 doi "https://doi.org/10.1097/00006676-200201000-00002" @default.
• W2056575247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11741177" @default.
• W2056575247 hasPublicationYear "2002" @default.
• W2056575247 type Work @default.
• W2056575247 sameAs 2056575247 @default.
• W2056575247 citedByCount "70" @default.
• W2056575247 countsByYear W20565752472012 @default.
• W2056575247 countsByYear W20565752472013 @default.
• W2056575247 countsByYear W20565752472014 @default.
• W2056575247 countsByYear W20565752472015 @default.
• W2056575247 countsByYear W20565752472016 @default.
• W2056575247 countsByYear W20565752472017 @default.
• W2056575247 countsByYear W20565752472018 @default.
• W2056575247 countsByYear W20565752472019 @default.
• W2056575247 countsByYear W20565752472020 @default.
• W2056575247 countsByYear W20565752472021 @default.
• W2056575247 countsByYear W20565752472022 @default.
• W2056575247 crossrefType "journal-article" @default.
• W2056575247 hasAuthorship W2056575247A5001558382 @default.
• W2056575247 hasAuthorship W2056575247A5018059398 @default.
• W2056575247 hasAuthorship W2056575247A5031869445 @default.
• W2056575247 hasAuthorship W2056575247A5037249662 @default.
• W2056575247 hasAuthorship W2056575247A5050450297 @default.
• W2056575247 hasAuthorship W2056575247A5051237706 @default.
• W2056575247 hasAuthorship W2056575247A5060268889 @default.
• W2056575247 hasAuthorship W2056575247A5063101360 @default.
• W2056575247 hasAuthorship W2056575247A5071801847 @default.
• W2056575247 hasAuthorship W2056575247A5082322650 @default.
• W2056575247 hasAuthorship W2056575247A5091598147 @default.
• W2056575247 hasConcept C121608353 @default.
• W2056575247 hasConcept C126322002 @default.
• W2056575247 hasConcept C134018914 @default.
• W2056575247 hasConcept C185592680 @default.
• W2056575247 hasConcept C2775967933 @default.
• W2056575247 hasConcept C2778875212 @default.
• W2056575247 hasConcept C2779281246 @default.
• W2056575247 hasConcept C2780210213 @default.
• W2056575247 hasConcept C55493867 @default.
• W2056575247 hasConcept C555293320 @default.
• W2056575247 hasConcept C62231903 @default.
• W2056575247 hasConcept C71924100 @default.
• W2056575247 hasConceptScore W2056575247C121608353 @default.
• W2056575247 hasConceptScore W2056575247C126322002 @default.
• W2056575247 hasConceptScore W2056575247C134018914 @default.
• W2056575247 hasConceptScore W2056575247C185592680 @default.
• W2056575247 hasConceptScore W2056575247C2775967933 @default.
• W2056575247 hasConceptScore W2056575247C2778875212 @default.
• W2056575247 hasConceptScore W2056575247C2779281246 @default.
• W2056575247 hasConceptScore W2056575247C2780210213 @default.
• W2056575247 hasConceptScore W2056575247C55493867 @default.
• W2056575247 hasConceptScore W2056575247C555293320 @default.
• W2056575247 hasConceptScore W2056575247C62231903 @default.
• W2056575247 hasConceptScore W2056575247C71924100 @default.
• W2056575247 hasIssue "1" @default.
• W2056575247 hasLocation W20565752471 @default.
• W2056575247 hasLocation W20565752472 @default.
• W2056575247 hasOpenAccess W2056575247 @default.
• W2056575247 hasPrimaryLocation W20565752471 @default.
• W2056575247 hasRelatedWork W2009275490 @default.
• W2056575247 hasRelatedWork W2025542867 @default.
• W2056575247 hasRelatedWork W2068118511 @default.
• W2056575247 hasRelatedWork W2069796876 @default.

• next