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- W2056578445 abstract "Introduction It's evident that abnormalities of subcortical brain structures asymmetry are related with schizophrenia pathogenesis. Objectives Basal ganglia participate in memory processes. Estimation of relationship between their asymmetry parameters and memory characteristics should be examined. Aims To investigate correlations between nucleus lentiformis (NL) MRI parameters and memory peculiarities (semantic aspect) in schizophrenia 96 patients and 51 controls were examined. Methods 3D MR images were acquired on magnet 0.5 Tomikon S50, Bruker (69 patients‘and 34 controls‘groups) and 1.5T GE Signa System (27 patients‘and 17 controls‘groups). Volumes (V) of left and right NL and their asymmetry coefficients (2 x (right NLV- left NLV) x 100/ (right NLV+left NLV),%) were calculated. Psychological pictogram method 1,2 estimating mnestic activity including semantic aspect was used. Quantitative (retention productivity score (RPS) was analyzed. Results Decreasing of the right (more prominent, p = 0.046, p = 0.044) and left NL (p = 0.048, p = 0.048) volumes were demonstrated in both patients groups. The RPS was less in both patients groups as compared with controls (p < 0.01). Correlation between NL asymmetry coefficients and RPS was revealed in patients underwent 0.5 and 1.5T scanners (r = -0.51, p < 0.05; r = - 0.57, p < 0.05 correspondingly). Conclusions The data confirm significance of brain asymmetry and memory dysfunction in etiology of schizophrenia." @default.
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- W2056578445 date "2011-03-01" @default.
- W2056578445 modified "2023-09-23" @default.
- W2056578445 title "FC02-06 - Correlations between nucleus lentiformis asymmetry parameters (MRI data) and memory characteristics (semantic aspect) in patients with schizophrenia" @default.
- W2056578445 doi "https://doi.org/10.1016/s0924-9338(11)73524-6" @default.
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