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- W2056580433 abstract "ATERNAL UNDERNUTRITION, EMBODIED BY SHORT stature and a low body mass index (BMI) and caused by chronic energy and micronutrient deficiencies, is highly prevalent in many developing countries. Short stature (145 cm) affects more than 10% of women of reproductive age across southcentral Asia, but only 1% to 2% in sub-Saharan Africa, whereas a low BMI (18.5) is found among 20% or more women in both regions. 1 Both indicators can predict adverse pregnancy outcomes. Maternal height is a strong predictor of birth size, independent of pre-pregnancy BMI and weight gain during pregnancy. Short maternal stature is highly associated with uterine volume and blood flow and is associated with risks of fetal growth restriction, cesarean delivery, 2 and cephalo-pelvic disproportion, the risk of which is likely modified by newborn size. 3 Of these 2 indices of undernutrition, attained adult height in women reflects a cumulative outcome measure of environmental exposures from fetal to adult life encompassing nutritional, infectious, sociocultural, and economic influences. The critical windows for linear growth include the fetal period, early childhood (0-24 months), and pubertal and adolescent periods, each of which influences attained adult height. The long-described theory of intergenerational cycle of growth failure posits that a small adult woman will deliver a small baby with fetal growth restriction, who will subsequently experience growth faltering as a child and low stature and body weight as an adolescent, ultimately leading to a small adult. 4 However, few empirical data have directly linked maternal stature to undernutrition over a generational cycle." @default.
- W2056580433 created "2016-06-24" @default.
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- W2056580433 date "2010-04-21" @default.
- W2056580433 modified "2023-10-06" @default.
- W2056580433 title "Maternal Height and Risk of Child Mortality and Undernutrition" @default.
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- W2056580433 doi "https://doi.org/10.1001/jama.2010.469" @default.
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