Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056580473> ?p ?o ?g. }
- W2056580473 endingPage "5349" @default.
- W2056580473 startingPage "5341" @default.
- W2056580473 abstract "Dipalmitoylphosphatidylcholine (DPPC) is the predominant lipid component in lung surfactant. In this study, the Langmuir monolayer of deuterated dipalmitoylphosphatidylcholine (DPPC-d62) in the liquid-expanded (LE) phase and the liquid-condensed (LC) phase has been investigated at the air-water interface with broad bandwidth sum frequency generation (BBSFG) spectroscopy combined with a Langmuir film balance. Four moieties of the DPPC molecule are probed by BBSFG: the terminal methyl (CD3) groups of the tails, the methylene (CD2) groups of the tails, the choline methyls (CH3) in the headgroup, and the phosphate in the headgroup. BBSFG spectra of the four DPPC moieties provide information about chain conformation, chain orientation, headgroup orientation, and headgroup hydration. These results provide a comprehensive picture of the DPPC phase behavior at the air-water interface. In the LE phase, the DPPC hydrocarbon chains are conformationally disordered with a significant number of gauche configurations. In the LC phase, the hydrocarbon chains are in an all-trans conformation and are tilted from the surface normal by 25 degrees. In addition, the orientations of the tail terminal methyl groups are found to remain nearly unchanged with the variation of surface area. Qualitative analysis of the BBSFG spectra of the choline methyl groups suggests that these methyl groups are tilted but lie somewhat parallel to the surface plane in both the LE and LC phases. The dehydration of the phosphate headgroup due to the LE-LC phase transition is observed through the frequency blue shift of the phosphate symmetric stretch in the fingerprint region. In addition, implications for lung surfactant function from this work are discussed." @default.
- W2056580473 created "2016-06-24" @default.
- W2056580473 creator A5048587663 @default.
- W2056580473 creator A5058209317 @default.
- W2056580473 date "2006-05-05" @default.
- W2056580473 modified "2023-10-16" @default.
- W2056580473 title "DPPC Langmuir Monolayer at the Air−Water Interface: Probing the Tail and Head Groups by Vibrational Sum Frequency Generation Spectroscopy" @default.
- W2056580473 cites W1518596711 @default.
- W2056580473 cites W1666553655 @default.
- W2056580473 cites W1913691314 @default.
- W2056580473 cites W1966774119 @default.
- W2056580473 cites W1966795721 @default.
- W2056580473 cites W1968833619 @default.
- W2056580473 cites W1970917597 @default.
- W2056580473 cites W1971040275 @default.
- W2056580473 cites W1973164211 @default.
- W2056580473 cites W1973188669 @default.
- W2056580473 cites W1975805501 @default.
- W2056580473 cites W1979219993 @default.
- W2056580473 cites W1980013521 @default.
- W2056580473 cites W1982949329 @default.
- W2056580473 cites W1983022201 @default.
- W2056580473 cites W1983393027 @default.
- W2056580473 cites W1984975103 @default.
- W2056580473 cites W1989243153 @default.
- W2056580473 cites W1989325801 @default.
- W2056580473 cites W1994014080 @default.
- W2056580473 cites W1996300479 @default.
- W2056580473 cites W1998476468 @default.
- W2056580473 cites W1999759414 @default.
- W2056580473 cites W2002650530 @default.
- W2056580473 cites W2004581014 @default.
- W2056580473 cites W2010000582 @default.
- W2056580473 cites W2010433544 @default.
- W2056580473 cites W2012222136 @default.
- W2056580473 cites W2013107255 @default.
- W2056580473 cites W2014799364 @default.
- W2056580473 cites W2015325185 @default.
- W2056580473 cites W2016989826 @default.
- W2056580473 cites W2020139835 @default.
- W2056580473 cites W2021246523 @default.
- W2056580473 cites W2022612929 @default.
- W2056580473 cites W2023209557 @default.
- W2056580473 cites W2024644634 @default.
- W2056580473 cites W2024874538 @default.
- W2056580473 cites W2025016594 @default.
- W2056580473 cites W2025233470 @default.
- W2056580473 cites W2026218538 @default.
- W2056580473 cites W2028250245 @default.
- W2056580473 cites W2036629638 @default.
- W2056580473 cites W2039778999 @default.
- W2056580473 cites W2042611887 @default.
- W2056580473 cites W2045596335 @default.
- W2056580473 cites W2045928693 @default.
- W2056580473 cites W2047501009 @default.
- W2056580473 cites W2048989814 @default.
- W2056580473 cites W2052412840 @default.
- W2056580473 cites W2054323323 @default.
- W2056580473 cites W2055950309 @default.
- W2056580473 cites W2062234578 @default.
- W2056580473 cites W2063312972 @default.
- W2056580473 cites W2063537903 @default.
- W2056580473 cites W2066512277 @default.
- W2056580473 cites W2068710356 @default.
- W2056580473 cites W2070101591 @default.
- W2056580473 cites W2070139685 @default.
- W2056580473 cites W2070508462 @default.
- W2056580473 cites W2071842104 @default.
- W2056580473 cites W2075684765 @default.
- W2056580473 cites W2076805254 @default.
- W2056580473 cites W2078367413 @default.
- W2056580473 cites W2079493449 @default.
- W2056580473 cites W2084679669 @default.
- W2056580473 cites W2085161139 @default.
- W2056580473 cites W2085326870 @default.
- W2056580473 cites W2085735627 @default.
- W2056580473 cites W2086064103 @default.
- W2056580473 cites W2088286547 @default.
- W2056580473 cites W2089578439 @default.
- W2056580473 cites W2090819119 @default.
- W2056580473 cites W2091487332 @default.
- W2056580473 cites W2091678002 @default.
- W2056580473 cites W2092249468 @default.
- W2056580473 cites W2093270959 @default.
- W2056580473 cites W2093419908 @default.
- W2056580473 cites W2097120859 @default.
- W2056580473 cites W2098908528 @default.
- W2056580473 cites W2104346372 @default.
- W2056580473 cites W2106171015 @default.
- W2056580473 cites W2108914108 @default.
- W2056580473 cites W2120560453 @default.
- W2056580473 cites W2120858662 @default.
- W2056580473 cites W2120908678 @default.
- W2056580473 cites W2130081721 @default.
- W2056580473 cites W2133566027 @default.
- W2056580473 cites W2133652131 @default.
- W2056580473 cites W2137419733 @default.
- W2056580473 cites W2146887604 @default.