Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056585294> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2056585294 endingPage "108" @default.
- W2056585294 startingPage "97" @default.
- W2056585294 abstract "We first review the concept of delta homeostasis as formulated in our 1974 model and as developed quantitatively by Borbely and colleagues in several versions of the two-process model. We illustrate difficulties in the application of this quantitative model to the negative delta rebound in the rat and we put forward additional evidence that the negative rebound is a pathological rather than a homeostatic response to sleep deprivation. We next review experiments on rats in which the waking metabolic rate of limbic structures was increased by blockade of the NMDA-gated cation channel with ketamine and MK-801. As predicted by the 1974 homeostatic model, NREM delta increased during subsequent sleep. However, it remains to be shown that this powerful effect is actually caused by the metabolic change and that it is an intensification of physiological sleep rather than a non-specific increase in EEG slow waves caused by neurotoxicity. We then outline our one-stimulus model of NREM/REM alternation. In this model NREM sleep is induced by periodic (neuroendocrine?) pulses. These pulses increase delta EEG amplitude and density, depress arousal level and inhibit neural activity. When the strength of the pulsatile stimulus falls below a critical level, REM emerges as neuronal escape. Last, we discuss the neurobiologic implications of two robust findings in experimental dream studies: the relation of dream reports to arousal and the consistent failure of controlled studies to demonstrate qualitative differences between NREM and REM mentation." @default.
- W2056585294 created "2016-06-24" @default.
- W2056585294 creator A5018917404 @default.
- W2056585294 creator A5028453647 @default.
- W2056585294 date "1995-07-01" @default.
- W2056585294 modified "2023-10-14" @default.
- W2056585294 title "Observations on delta homeostasis, the one-stimulus model of NREM-REM alternation and the neurobiologic implications of experimental dream studies" @default.
- W2056585294 cites W1750887975 @default.
- W2056585294 cites W1920879160 @default.
- W2056585294 cites W1963859198 @default.
- W2056585294 cites W1971690982 @default.
- W2056585294 cites W1986532362 @default.
- W2056585294 cites W1997338221 @default.
- W2056585294 cites W1997596070 @default.
- W2056585294 cites W2001282658 @default.
- W2056585294 cites W2007261661 @default.
- W2056585294 cites W2008459537 @default.
- W2056585294 cites W2022654634 @default.
- W2056585294 cites W2023414805 @default.
- W2056585294 cites W2025011978 @default.
- W2056585294 cites W2029213783 @default.
- W2056585294 cites W2037822546 @default.
- W2056585294 cites W2042276685 @default.
- W2056585294 cites W2043625816 @default.
- W2056585294 cites W2045629189 @default.
- W2056585294 cites W2047004412 @default.
- W2056585294 cites W2053194133 @default.
- W2056585294 cites W2056607297 @default.
- W2056585294 cites W2078337693 @default.
- W2056585294 cites W2079179784 @default.
- W2056585294 cites W2079856030 @default.
- W2056585294 cites W2082824503 @default.
- W2056585294 cites W2086486843 @default.
- W2056585294 cites W2088574810 @default.
- W2056585294 cites W2090891380 @default.
- W2056585294 cites W2091904733 @default.
- W2056585294 cites W2129937345 @default.
- W2056585294 cites W2135186097 @default.
- W2056585294 cites W2144097932 @default.
- W2056585294 cites W2165892338 @default.
- W2056585294 cites W2310604212 @default.
- W2056585294 cites W2406124037 @default.
- W2056585294 cites W2421974757 @default.
- W2056585294 cites W2429194718 @default.
- W2056585294 cites W2465460230 @default.
- W2056585294 cites W2472680777 @default.
- W2056585294 cites W2474194454 @default.
- W2056585294 doi "https://doi.org/10.1016/0166-4328(95)00010-q" @default.
- W2056585294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7546323" @default.
- W2056585294 hasPublicationYear "1995" @default.
- W2056585294 type Work @default.
- W2056585294 sameAs 2056585294 @default.
- W2056585294 citedByCount "50" @default.
- W2056585294 countsByYear W20565852942012 @default.
- W2056585294 countsByYear W20565852942013 @default.
- W2056585294 countsByYear W20565852942016 @default.
- W2056585294 countsByYear W20565852942020 @default.
- W2056585294 countsByYear W20565852942021 @default.
- W2056585294 crossrefType "journal-article" @default.
- W2056585294 hasAuthorship W2056585294A5018917404 @default.
- W2056585294 hasAuthorship W2056585294A5028453647 @default.
- W2056585294 hasConcept C15744967 @default.
- W2056585294 hasConcept C169760540 @default.
- W2056585294 hasConcept C180747234 @default.
- W2056585294 hasConcept C20566671 @default.
- W2056585294 hasConcept C2779918689 @default.
- W2056585294 hasConcept C36951298 @default.
- W2056585294 hasConcept C522805319 @default.
- W2056585294 hasConceptScore W2056585294C15744967 @default.
- W2056585294 hasConceptScore W2056585294C169760540 @default.
- W2056585294 hasConceptScore W2056585294C180747234 @default.
- W2056585294 hasConceptScore W2056585294C20566671 @default.
- W2056585294 hasConceptScore W2056585294C2779918689 @default.
- W2056585294 hasConceptScore W2056585294C36951298 @default.
- W2056585294 hasConceptScore W2056585294C522805319 @default.
- W2056585294 hasIssue "1-2" @default.
- W2056585294 hasLocation W20565852941 @default.
- W2056585294 hasLocation W20565852942 @default.
- W2056585294 hasOpenAccess W2056585294 @default.
- W2056585294 hasPrimaryLocation W20565852941 @default.
- W2056585294 hasRelatedWork W1581909948 @default.
- W2056585294 hasRelatedWork W1974545901 @default.
- W2056585294 hasRelatedWork W2055425736 @default.
- W2056585294 hasRelatedWork W2132865443 @default.
- W2056585294 hasRelatedWork W2438706126 @default.
- W2056585294 hasRelatedWork W2505776173 @default.
- W2056585294 hasRelatedWork W2954331597 @default.
- W2056585294 hasRelatedWork W3034213934 @default.
- W2056585294 hasRelatedWork W3100884300 @default.
- W2056585294 hasRelatedWork W3156682619 @default.
- W2056585294 hasVolume "69" @default.
- W2056585294 isParatext "false" @default.
- W2056585294 isRetracted "false" @default.
- W2056585294 magId "2056585294" @default.
- W2056585294 workType "article" @default.