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• W2056585387 abstract "AimsApolipoprotein E (apoE) may act as a vasculoprotective factor by promoting plasma lipid clearance and cholesterol efflux. Moreover, apoE accumulates at sites of vascular injury and modulates the effect of growth factors on smooth muscle cells (SMCs). Experimental data suggested that hypothalamic apoE expression is reduced in obesity and associated with leptin resistance. In this study, we examined the role of apoE in mediating the effects of leptin on vascular lesion formation." @default.
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• W2056585387 date "2013-05-30" @default.
• W2056585387 modified "2023-09-27" @default.
• W2056585387 title "Leptin promotes neointima formation and smooth muscle cell proliferation via NADPH oxidase activation and signalling in caveolin-rich microdomains" @default.
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• W2056585387 doi "https://doi.org/10.1093/cvr/cvt126" @default.
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