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- W2056594362 abstract "The oxidation of l-leucine-1-14C and l-leucine-U-14C to 14CO2 in liver and kidney tissue of the rat has been investigated. Kidney tissue was found to be the more active. Slices, homogenates, and mitochondria were able to oxidize this amino acid. Kidney slices converted all six carbon atoms to CO2 with approximately equal facility, but homogenates and mitochondria showed some loss of ability to oxidize C2-C6 to CO2. The results obtained using isolated mitochondrial systems are consistent with an initial deamination by transamination with α-ketoglutarate, an oxidative decarboxylation of the keto acid formed, followed by oxidation of the carbon skeleton by a process coupled with oxidative phosphorylation." @default.
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- W2056594362 date "1967-11-01" @default.
- W2056594362 modified "2023-09-25" @default.
- W2056594362 title "Oxidation of leucine by rat liver and kidney" @default.
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- W2056594362 doi "https://doi.org/10.1016/0003-9861(67)90216-0" @default.
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