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- W2056595307 abstract "Obesity is associated with an increased risk of developing co-morbidities such as cardiovascular disease and type 2 diabetes. However, not all obese subjects have an increased risk of developing these co-morbidities. It has been suggested that triacylglycerols stored in subcutaneous adipose tissue protect the body against the accumulation of triacylglycerols in other tissues such as heart, skeletal muscle, liver and the β-cells of the endocrine pancreas which would impair their function. This phenomenon of lipotoxicity probably explains the defects in insulin action and insulin secretion seen in type 2 diabetes and perhaps impaired diastolic function of the heart. A distinction needs to be drawn between this ‘unhealthy’ ectopic body fat which is detrimental to human health and ‘healthy’ subcutaneous body fat which may protect it." @default.
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- W2056595307 date "2011-09-01" @default.
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- W2056595307 title "Healthy and unhealthy body fat" @default.
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- W2056595307 doi "https://doi.org/10.1002/lite.201100134" @default.
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