FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056599263> ?p ?o ?g. }

• W2056599263 endingPage "3910" @default.
• W2056599263 startingPage "3903" @default.
• W2056599263 abstract "Radioiodine has been in use for over as a treatment for hyperthyroidism. Major changes in clinical practice have led to accurate dosimetry capable of avoiding the risks of adverse effects and the optimization of the treatment. The aim of this study was to test the capability of a radiobiological model, based on normal tissue complication probability (NTCP), to predict the outcome after oral therapeutic administration. Following dosimetric study, 79 patients underwent treatment for hyperthyroidism using radioiodine and then 67 had at least a one‐year follow up. The delivered dose was calculated using the MIRD formula, taking into account the measured maximum uptake of administered iodine transferred to the thyroid, U0, and the effective clearance rate, and target mass. The dose was converted to normalized total dose delivered at per fraction . Furthermore, the method to take into account the reduction of the mass of the gland during radioiodine therapy was also applied. The clinical outcome and dosimetric parameters were analyzed in order to study the dose‐response relationship for hypothyroidism. The and parameters of the NTCP model approach were then estimated using the likelihood method. The , expressed as , resulted in (95% C.I.: ) and (95% C.I.: ) for patients affected by Graves or autonomous/multinodular disease, respectively. This supports the clinical evidence that Graves’ disease should be characterized by more radiosensitive cells compared to autonomous nodules. The parameter for all patients was 0.27 (95% C.I.: 0.22–0.36). These parameters were compared with those reported in the literature for hypothyroidism induced after external beam radiotherapy. The NTCP model correctly predicted the clinical outcome after the therapeutic administration of radioiodine in our series." @default.
• W2056599263 created "2016-06-24" @default.
• W2056599263 creator A5013993544 @default.
• W2056599263 creator A5015554984 @default.
• W2056599263 creator A5030882491 @default.
• W2056599263 creator A5044463093 @default.
• W2056599263 creator A5085164215 @default.
• W2056599263 creator A5089554789 @default.
• W2056599263 date "2008-08-07" @default.
• W2056599263 modified "2023-09-26" @default.
• W2056599263 title "A NTCP approach for estimating the outcome in radioiodine treatment of hyperthyroidism" @default.
• W2056599263 cites W1964142614 @default.
• W2056599263 cites W1964426807 @default.
• W2056599263 cites W1965484999 @default.
• W2056599263 cites W1974933152 @default.
• W2056599263 cites W1979071351 @default.
• W2056599263 cites W1984273763 @default.
• W2056599263 cites W1984763462 @default.
• W2056599263 cites W1988024604 @default.
• W2056599263 cites W1991079477 @default.
• W2056599263 cites W1992487094 @default.
• W2056599263 cites W1996643840 @default.
• W2056599263 cites W2000877831 @default.
• W2056599263 cites W2004618544 @default.
• W2056599263 cites W2006591296 @default.
• W2056599263 cites W2013352777 @default.
• W2056599263 cites W2020924677 @default.
• W2056599263 cites W2030616688 @default.
• W2056599263 cites W2033456044 @default.
• W2056599263 cites W2040423852 @default.
• W2056599263 cites W2057827381 @default.
• W2056599263 cites W2062220131 @default.
• W2056599263 cites W2064969958 @default.
• W2056599263 cites W2069425825 @default.
• W2056599263 cites W2069942898 @default.
• W2056599263 cites W2095024727 @default.
• W2056599263 cites W2097512974 @default.
• W2056599263 cites W2137061036 @default.
• W2056599263 cites W2211182010 @default.
• W2056599263 cites W4241723568 @default.
• W2056599263 cites W2078131603 @default.
• W2056599263 doi "https://doi.org/10.1118/1.2964089" @default.
• W2056599263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18841841" @default.
• W2056599263 hasPublicationYear "2008" @default.
• W2056599263 type Work @default.
• W2056599263 sameAs 2056599263 @default.
• W2056599263 citedByCount "7" @default.
• W2056599263 countsByYear W20565992632012 @default.
• W2056599263 countsByYear W20565992632013 @default.
• W2056599263 countsByYear W20565992632014 @default.
• W2056599263 countsByYear W20565992632015 @default.
• W2056599263 countsByYear W20565992632021 @default.
• W2056599263 crossrefType "journal-article" @default.
• W2056599263 hasAuthorship W2056599263A5013993544 @default.
• W2056599263 hasAuthorship W2056599263A5015554984 @default.
• W2056599263 hasAuthorship W2056599263A5030882491 @default.
• W2056599263 hasAuthorship W2056599263A5044463093 @default.
• W2056599263 hasAuthorship W2056599263A5085164215 @default.
• W2056599263 hasAuthorship W2056599263A5089554789 @default.
• W2056599263 hasConcept C126322002 @default.
• W2056599263 hasConcept C191897082 @default.
• W2056599263 hasConcept C192562407 @default.
• W2056599263 hasConcept C197934379 @default.
• W2056599263 hasConcept C2779761222 @default.
• W2056599263 hasConcept C2989005 @default.
• W2056599263 hasConcept C3018694869 @default.
• W2056599263 hasConcept C509974204 @default.
• W2056599263 hasConcept C526584372 @default.
• W2056599263 hasConcept C539932907 @default.
• W2056599263 hasConcept C71924100 @default.
• W2056599263 hasConcept C75088862 @default.
• W2056599263 hasConcept C81182388 @default.
• W2056599263 hasConceptScore W2056599263C126322002 @default.
• W2056599263 hasConceptScore W2056599263C191897082 @default.
• W2056599263 hasConceptScore W2056599263C192562407 @default.
• W2056599263 hasConceptScore W2056599263C197934379 @default.
• W2056599263 hasConceptScore W2056599263C2779761222 @default.
• W2056599263 hasConceptScore W2056599263C2989005 @default.
• W2056599263 hasConceptScore W2056599263C3018694869 @default.
• W2056599263 hasConceptScore W2056599263C509974204 @default.
• W2056599263 hasConceptScore W2056599263C526584372 @default.
• W2056599263 hasConceptScore W2056599263C539932907 @default.
• W2056599263 hasConceptScore W2056599263C71924100 @default.
• W2056599263 hasConceptScore W2056599263C75088862 @default.
• W2056599263 hasConceptScore W2056599263C81182388 @default.
• W2056599263 hasIssue "9" @default.
• W2056599263 hasLocation W20565992631 @default.
• W2056599263 hasLocation W20565992632 @default.
• W2056599263 hasOpenAccess W2056599263 @default.
• W2056599263 hasPrimaryLocation W20565992631 @default.
• W2056599263 hasRelatedWork W1970090090 @default.
• W2056599263 hasRelatedWork W1979071351 @default.
• W2056599263 hasRelatedWork W2404714461 @default.
• W2056599263 hasRelatedWork W2511536138 @default.
• W2056599263 hasRelatedWork W2511944242 @default.
• W2056599263 hasRelatedWork W2590001245 @default.
• W2056599263 hasRelatedWork W2748952813 @default.
• W2056599263 hasRelatedWork W2909485130 @default.

• next