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• W2056607957 endingPage "353" @default.
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• W2056607957 abstract "SUMMARY Two-hundred MRSA strains from inpatients with healthcare-associated (HA) and 100 MRSA strains from outpatients with community-associated (CA) skin and soft tissue infections (SSTIs) were tested for antimicrobial susceptibility, staphylococcal cassette chromosome mec (SCC mec ) typing, Panton–Valentine leucocidin (PVL) toxin, seh and arcA genes. Based on SCC mec typing, HA-MRSA isolates were further divided into HA-SCC mec I/II/III MRSA and HA-SCC mec IV/V MRSA, and CA-MRSA isolates into CA-SCC mec I/II/III MRSA and CA-SCC mec IV/V MRSA. SCC mec types were further characterized by pulsed-field gel electrophoresis, spa typing and multi-locus sequence typing. Seventy-five (37·5%) HA-MRSA isolates and 83/100 CA-MRSA isolates were SCC mec IV/V genotype. HA-SCC mec IV/V MRSA was associated with malignancy ( P = 0·03) and bone fractures ( P = 0·02) compared to CA-SCC mec IV/V MRSA. HA-SCC mec IV/V MRSA was associated with PVL gene carriage compared to HA-SCC mec I/II/III MRSA ( P < 0·001). ST22-MRSA-IV (EMRSA-15), ST772-MRSA-V, and ST36-MRSA-IV and ST239:EMRSA-I:III were the major clones identified. Our study documents the emergence of SCC mec IV and SCC mec V MRSA clones in an Indian hospital." @default.
• W2056607957 created "2016-06-24" @default.
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• W2056607957 date "2014-04-02" @default.
• W2056607957 modified "2023-10-01" @default.
• W2056607957 title "Dissemination of methicillin-resistant<i>Staphylococcus aureus</i>SCC<i>mec</i>type IV and SCC<i>mec</i>type V epidemic clones in a tertiary hospital: challenge to infection control" @default.
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• W2056607957 doi "https://doi.org/10.1017/s095026881400065x" @default.
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