Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056644955> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2056644955 endingPage "407A" @default.
- W2056644955 startingPage "407A" @default.
- W2056644955 abstract "Surfactant apolipoprotein A (apo A) is a major lipid binding protein and an active component of pulmonary surfactant. Apo A was purified from human alveolar lavage, amniotic fluid and alveolar proteinosis fluid. Two major forms were identified by silver stain and immunoblot: apo A2 (Mr=34,000), apo A1 (Mr=28,000). Larger forms were reduced to Mr=28;000 by treatment with endoglycosidase F demonstrating complex N-linked oligosaccharide. Isoelectric point was increased by neuraminidase demonstrating presence of sialic acid. Poly A mRNA isolated from adult human lung was translated in vitro; primary translation products were identified at Mr=28,000. Homology between Mr=34,000 and 28,000 was confirmed by analysis of 2D tryptic peptide maps of apo A1 and A2 which were identical, thus providing evidence that apo A results from processing of the Mr=28,000 precursor by addition of carbohydrate. Amino acid composition of purified apo A was rich in glycine and contained a large portion of collagen-like sequence. Apoproteins A were identified in surfactant from amniotic fluid, normal adult lung lavage, human cadaver lavage and material obtained from a patient with alveolar proteinosis. Apo A was identified in all of these samples by silver stain and immunoblot analysis. Alveolar proteinosis fluid contained acidic aggregates whose peptide maps were identical to apo A from normal human lung lavage. These studies clarify the identity of human apo A, a complex N-linked glycoprotein derived from a polypeptide of Mr=28,000." @default.
- W2056644955 created "2016-06-24" @default.
- W2056644955 creator A5001813162 @default.
- W2056644955 creator A5010802703 @default.
- W2056644955 creator A5028477677 @default.
- W2056644955 creator A5055786810 @default.
- W2056644955 date "1985-04-01" @default.
- W2056644955 modified "2023-10-18" @default.
- W2056644955 title "1780 HUMAN SURFACTANT ASSOCIATED APOLIPOPROTEIN A: MOLECULAR COMPOSITION AND PRIMARY TRANSLATION PRODUCTS" @default.
- W2056644955 doi "https://doi.org/10.1203/00006450-198504000-01798" @default.
- W2056644955 hasPublicationYear "1985" @default.
- W2056644955 type Work @default.
- W2056644955 sameAs 2056644955 @default.
- W2056644955 citedByCount "1" @default.
- W2056644955 countsByYear W20566449552022 @default.
- W2056644955 crossrefType "journal-article" @default.
- W2056644955 hasAuthorship W2056644955A5001813162 @default.
- W2056644955 hasAuthorship W2056644955A5010802703 @default.
- W2056644955 hasAuthorship W2056644955A5028477677 @default.
- W2056644955 hasAuthorship W2056644955A5055786810 @default.
- W2056644955 hasBestOaLocation W20566449551 @default.
- W2056644955 hasConcept C126322002 @default.
- W2056644955 hasConcept C153911025 @default.
- W2056644955 hasConcept C172680121 @default.
- W2056644955 hasConcept C181199279 @default.
- W2056644955 hasConcept C185592680 @default.
- W2056644955 hasConcept C2777714996 @default.
- W2056644955 hasConcept C2778163477 @default.
- W2056644955 hasConcept C2778194526 @default.
- W2056644955 hasConcept C2778972612 @default.
- W2056644955 hasConcept C2779234561 @default.
- W2056644955 hasConcept C54355233 @default.
- W2056644955 hasConcept C55493867 @default.
- W2056644955 hasConcept C58226133 @default.
- W2056644955 hasConcept C62746215 @default.
- W2056644955 hasConcept C71924100 @default.
- W2056644955 hasConcept C86803240 @default.
- W2056644955 hasConcept C96294017 @default.
- W2056644955 hasConceptScore W2056644955C126322002 @default.
- W2056644955 hasConceptScore W2056644955C153911025 @default.
- W2056644955 hasConceptScore W2056644955C172680121 @default.
- W2056644955 hasConceptScore W2056644955C181199279 @default.
- W2056644955 hasConceptScore W2056644955C185592680 @default.
- W2056644955 hasConceptScore W2056644955C2777714996 @default.
- W2056644955 hasConceptScore W2056644955C2778163477 @default.
- W2056644955 hasConceptScore W2056644955C2778194526 @default.
- W2056644955 hasConceptScore W2056644955C2778972612 @default.
- W2056644955 hasConceptScore W2056644955C2779234561 @default.
- W2056644955 hasConceptScore W2056644955C54355233 @default.
- W2056644955 hasConceptScore W2056644955C55493867 @default.
- W2056644955 hasConceptScore W2056644955C58226133 @default.
- W2056644955 hasConceptScore W2056644955C62746215 @default.
- W2056644955 hasConceptScore W2056644955C71924100 @default.
- W2056644955 hasConceptScore W2056644955C86803240 @default.
- W2056644955 hasConceptScore W2056644955C96294017 @default.
- W2056644955 hasIssue "4" @default.
- W2056644955 hasLocation W20566449551 @default.
- W2056644955 hasOpenAccess W2056644955 @default.
- W2056644955 hasPrimaryLocation W20566449551 @default.
- W2056644955 hasRelatedWork W1996421710 @default.
- W2056644955 hasRelatedWork W2001597538 @default.
- W2056644955 hasRelatedWork W2014012487 @default.
- W2056644955 hasRelatedWork W2064112767 @default.
- W2056644955 hasRelatedWork W2074983793 @default.
- W2056644955 hasRelatedWork W2093248731 @default.
- W2056644955 hasRelatedWork W2414385197 @default.
- W2056644955 hasRelatedWork W2612138326 @default.
- W2056644955 hasRelatedWork W2738985830 @default.
- W2056644955 hasRelatedWork W4245231077 @default.
- W2056644955 hasVolume "19" @default.
- W2056644955 isParatext "false" @default.
- W2056644955 isRetracted "false" @default.
- W2056644955 magId "2056644955" @default.
- W2056644955 workType "article" @default.