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• W2056698617 abstract "The prenatal survival frequency of reciprocal F1-hybrid embryos of C57BL6/J and AKR/J mice differ remarkably (15% us 49%) indicating a strong maternal effect. Transfer of the reciprocal F1-embryos at day 4 p.c. was performed either into foster mothers of their paternal or their maternal strain in order to define the influence of the embryonic plasmatype and the maternal environment on the prenatal survival frequency of those F1-embryos. The reciprocal F1-embryos at day 4 p.c. differ according to their mother's strain in numbers of infertitized and degenerated ova, indicating a strong extrachromosomal influence on the prenatal loss, i.e. an influence rather of the embryos themselves than of the maternal environment. The number of implantation sites after transfer of the reciprocal F1-embryos differs according to the genotype of the foster mother, indicating a stronger influence of the maternal environment during implantation. Despite a small number of live fetuses after transfer, there is a significant difference of healthy fetuses according to the type of the reciprocal F1-embryos, indicating a stronger influence of the embryos themselves on the post-impluntative survival frequency. The results support the hypothesis that prenatal loss in isogenic embryos is caused to a heh degree by cytoplasmic factors of the ova. Pränatale Dberlebensrate bei reziproken F1-Hybridmäusen — verursacht durch embryonale Faktoren und den Genotyp der uterinen., Amme Die pränatalen Überlebensraten von reziproken F1-Hybriden von C57BL6/J- und AKR/J-Embryonen unterscheiden sich erheblich (15% gegenüber 49%); das deutet auf starken maternalen Effekt hin. Wir transferierten reziproke F1-Embryonen vom Tag 4 p.c. entweder in Empfängermütter des maternalen oder paternalen Stammes, um den Einfluβp von embryonalen Faktoren und der maternalen Umgebung auf die pränatale Überlebensrate dieser F1-Embryonen am 17. Gestationstag zu untersuchen. Am Tag 4 p.c. differiert die Anzahl von unbefruchteten und degenerierten Eizellen zwischen den reziproken F1-Hybriden gemäβp ihrem maternalen Stamm. Das zeigt einen starken extrachromosomalen, wahrscheinlich mit dem Zytoplasma der Eizelle vermittelten Einfluβ auf die präimplantative Verlustrate. Am 1 7. Tag differiert dagegen die Anzahl der Implantationsstellen nach Transfer von reziproken F1-Embryonen gemäβ dem Genotyp der uterinen., Amme, was auf einen stärkeren Einfluβ der maternalen Umgebung während der implantation schlieβen läβt. Nur wenige Feten entwickeln sich nach Transfer vollständig. Die Differenr ihrer Anzahl rwischen den beiden F1-Hybriden zeigt, daβ die postimplantative Überlebensrate der Feten wieder besonders von ihnen selbst beeinfluβt wird. Diese Resultate untermauern die Hypothese, daβ die pranatale Verlustrate bei isogenen, reziproken F1-Hybriden in hohem Maβe durch zytoplasmi-sche Faktoren der Eizellen verursacht wird." @default.
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• W2056698617 date "1986-07-01" @default.
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• W2056698617 title "Prenatal survival frequency of reciprocal F1-hybrids in inbred mice caused both by embryonic factors and genotype of foster mother" @default.
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• W2056698617 doi "https://doi.org/10.1111/j.1439-0531.1986.tb01493.x" @default.
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