FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056718373> ?p ?o ?g. }

• W2056718373 endingPage "1091" @default.
• W2056718373 startingPage "1087" @default.
• W2056718373 abstract "Aspergillus fumigatus secretes an array of antigenic molecules in vitro and in vivo. Recent progresses have been made in the characterization and standardization of A. fumigatus antigens useful for the serodiagnosis of aspergillosis. The chymotrypsin antigen has been purified and can be utilized for the diagnosis of aspergillosis occurring in patients with an immunocompetent B cell population. In the case of immunosuppressed patients suffering from invasive aspergillosis, new methods have been developed to detect the galactofuran containing antigen in the serum. The chemical configuration of this molecule is now known. In contrast to their potential in diagnosis, very little progress has been made on the study of the biochemical and pathoimmunological role of these antigens during the infection process. Two reasons can be advanced for this lack of understanding of the virulence determinants. First of all, antigens studied have been produced in vitro in a dextrose rich medium where pH reaches a value below 5 at maximal growth. These culture conditions are very different from the nutritional environment of the lung, which is a protein-based medium with a slightly basic pH. Antigens expressed under these nutritional conditions are very different from the ones detected in vitro. Second, A. fumigatus is an opportunistic fungus which is characterized by a multifactorial virulence. Gene disruption strategy is not adequate to discriminate the role of a factor in the virulence of the fungus. In contrast, as shown by the studies on two toxins of A. fumigatus, a direct effect of an antigen can be seen directly when several fungal molecules are tested in conjunction on host cells. Key words: Aspergillus fumigatus, antigen, invasive aspergillosis, galactomannan, protease." @default.
• W2056718373 created "2016-06-24" @default.
• W2056718373 creator A5003385861 @default.
• W2056718373 creator A5010149045 @default.
• W2056718373 creator A5016174025 @default.
• W2056718373 creator A5045007430 @default.
• W2056718373 creator A5055434923 @default.
• W2056718373 creator A5071439209 @default.
• W2056718373 creator A5077227657 @default.
• W2056718373 creator A5079849834 @default.
• W2056718373 creator A5089646950 @default.
• W2056718373 date "1995-12-31" @default.
• W2056718373 modified "2023-09-26" @default.
• W2056718373 title "Antigens ofAspergillus fumigatusexpressed during infection" @default.
• W2056718373 cites W1489680101 @default.
• W2056718373 cites W1568021747 @default.
• W2056718373 cites W1769591236 @default.
• W2056718373 cites W1915036617 @default.
• W2056718373 cites W1977651472 @default.
• W2056718373 cites W1984331205 @default.
• W2056718373 cites W2003288862 @default.
• W2056718373 cites W2010125102 @default.
• W2056718373 cites W2012386851 @default.
• W2056718373 cites W2044078875 @default.
• W2056718373 cites W2070345824 @default.
• W2056718373 cites W2073340716 @default.
• W2056718373 cites W2095268847 @default.
• W2056718373 cites W2110701053 @default.
• W2056718373 cites W2123332089 @default.
• W2056718373 cites W2124804490 @default.
• W2056718373 cites W2142331524 @default.
• W2056718373 cites W2144526814 @default.
• W2056718373 cites W2151544982 @default.
• W2056718373 cites W2157885858 @default.
• W2056718373 cites W2289297799 @default.
• W2056718373 cites W4211019915 @default.
• W2056718373 cites W4236490130 @default.
• W2056718373 cites W4254056239 @default.
• W2056718373 doi "https://doi.org/10.1139/b95-362" @default.
• W2056718373 hasPublicationYear "1995" @default.
• W2056718373 type Work @default.
• W2056718373 sameAs 2056718373 @default.
• W2056718373 citedByCount "5" @default.
• W2056718373 crossrefType "journal-article" @default.
• W2056718373 hasAuthorship W2056718373A5003385861 @default.
• W2056718373 hasAuthorship W2056718373A5010149045 @default.
• W2056718373 hasAuthorship W2056718373A5016174025 @default.
• W2056718373 hasAuthorship W2056718373A5045007430 @default.
• W2056718373 hasAuthorship W2056718373A5055434923 @default.
• W2056718373 hasAuthorship W2056718373A5071439209 @default.
• W2056718373 hasAuthorship W2056718373A5077227657 @default.
• W2056718373 hasAuthorship W2056718373A5079849834 @default.
• W2056718373 hasAuthorship W2056718373A5089646950 @default.
• W2056718373 hasConcept C104317684 @default.
• W2056718373 hasConcept C147483822 @default.
• W2056718373 hasConcept C150903083 @default.
• W2056718373 hasConcept C202751555 @default.
• W2056718373 hasConcept C203014093 @default.
• W2056718373 hasConcept C207001950 @default.
• W2056718373 hasConcept C2776391196 @default.
• W2056718373 hasConcept C2779787849 @default.
• W2056718373 hasConcept C2781090273 @default.
• W2056718373 hasConcept C2908647359 @default.
• W2056718373 hasConcept C55493867 @default.
• W2056718373 hasConcept C60987743 @default.
• W2056718373 hasConcept C71924100 @default.
• W2056718373 hasConcept C86803240 @default.
• W2056718373 hasConcept C89423630 @default.
• W2056718373 hasConcept C99454951 @default.
• W2056718373 hasConceptScore W2056718373C104317684 @default.
• W2056718373 hasConceptScore W2056718373C147483822 @default.
• W2056718373 hasConceptScore W2056718373C150903083 @default.
• W2056718373 hasConceptScore W2056718373C202751555 @default.
• W2056718373 hasConceptScore W2056718373C203014093 @default.
• W2056718373 hasConceptScore W2056718373C207001950 @default.
• W2056718373 hasConceptScore W2056718373C2776391196 @default.
• W2056718373 hasConceptScore W2056718373C2779787849 @default.
• W2056718373 hasConceptScore W2056718373C2781090273 @default.
• W2056718373 hasConceptScore W2056718373C2908647359 @default.
• W2056718373 hasConceptScore W2056718373C55493867 @default.
• W2056718373 hasConceptScore W2056718373C60987743 @default.
• W2056718373 hasConceptScore W2056718373C71924100 @default.
• W2056718373 hasConceptScore W2056718373C86803240 @default.
• W2056718373 hasConceptScore W2056718373C89423630 @default.
• W2056718373 hasConceptScore W2056718373C99454951 @default.
• W2056718373 hasIssue "S1" @default.
• W2056718373 hasLocation W20567183731 @default.
• W2056718373 hasOpenAccess W2056718373 @default.
• W2056718373 hasPrimaryLocation W20567183731 @default.
• W2056718373 hasRelatedWork W1598333916 @default.
• W2056718373 hasRelatedWork W1963570707 @default.
• W2056718373 hasRelatedWork W2003364903 @default.
• W2056718373 hasRelatedWork W2043027151 @default.
• W2056718373 hasRelatedWork W2046533420 @default.
• W2056718373 hasRelatedWork W2066731876 @default.
• W2056718373 hasRelatedWork W2090677789 @default.
• W2056718373 hasRelatedWork W2156611837 @default.
• W2056718373 hasRelatedWork W2335756740 @default.

• next