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- W2056776711 abstract "In human brain tissues from patients dying with cerebral infarction, hypertensive encephalopathy, Alzheimer's disease, Huntington's disease, frontotemporal dementia, and Creutzfeldt-Jakob disease there is an activation of astrocytes. Such activated astrocytes display GFAP and strong 5-HT(2A), but not 5-HT(2B) or 5-HT(2C), receptor immunoreactivity; this 5-HT(2A) reaction has not been observed in normal, nonactivated astrocytes. It is suggested that an up-regulation of 5-HT(2A) receptors may be part of an early response reaction in astrocytes, possibly designed to maintain homeostasis or to induce secondary message pathways involving trophic factors or glycogenolysis." @default.
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- W2056776711 date "1999-08-01" @default.
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- W2056776711 title "Activated Astrocytes Display Increased 5-HT2a Receptor Expression in Pathological States" @default.
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- W2056776711 doi "https://doi.org/10.1006/exnr.1999.7105" @default.
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