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• W2056802003 abstract "The immunization of a (BALB/c × C57BL/6) FI mouse with murine transfectants expressing the HLA-B27 antigen resulted in a panel of polymorphic monoclonal antibodies with specificity for HLA-B27 and some additional HLA-antigens. Specificity of the antibodies was defined by cytofluorometric analysis on a panel of lymphoblastoid cell lines (LCL) derived from HLA typed individuals. Three of these antibodies are cytotoxiC, and one of them inhibits B27-specific T cell cytotoxicity. Our results indicate that HLA-class I transfectants could be used to generate polymorphic antibodies, and that these antibodies may be helpful for HLA typing and for definition of epitopes recognized by T cells." @default.
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• W2056802003 date "1989-05-01" @default.
• W2056802003 modified "2023-10-14" @default.
• W2056802003 title "Expression and immunogenicity of HLA-B27 in high-transfection recipient P815: a new method to induce monoclonal antibodies directed against HLA-B27" @default.
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• W2056802003 doi "https://doi.org/10.1111/j.1399-0039.1989.tb01702.x" @default.
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