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- W2056864816 abstract "A potent lanthanide chelate, fulfilling the requirements for the development of MRI contrast agents or luminescent probes, was armed with alkyne groups. We then implemented a click methodology to graft the bifunctional ligand to azide-containing glucoside and maltoside scaffolds. The resulting hydrophilic glycoconjugates retained the ligand binding capacity for Eu3+ or Tb3+ ion as evidenced by the number of bound water molecules to the lanthanide ion. Divalent Eu3+ and Tb3+ complexes were shown to double the brightness of the emitted fluorescent signal compared to its monovalent derivatives. Designing multivalent lanthanide luminescent probes would enable the fluorescent signal of labeled biomolecules to be enhanced." @default.
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- W2056864816 date "2012-04-01" @default.
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- W2056864816 title "Lanthanide(III) complexes of pyridine–tetraacetic acid-glycoconjugates: Synthesis and luminescence studies of mono and divalent derivatives" @default.
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- W2056864816 doi "https://doi.org/10.1016/j.bmcl.2012.03.003" @default.
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