FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056911218> ?p ?o ?g. }

• W2056911218 endingPage "146" @default.
• W2056911218 startingPage "133" @default.
• W2056911218 abstract "The recently solved X-ray structure of the dimerization region (“leucine zipper”) of the yeast transcriptional activator GCN4 (O'Shea, E. K., Klemm, J. D., Kim, P. S., Alber, T. Science 254:539–544, 1991) is compared to previously predicted models which had been obtained by a conformational search procedure employing simulated annealing without any knowledge of the crystal coordinates (Nilges, M., Brünger, A. T. Protein Eng. 4:649–659,1991). During the course of the simulated annealing procedure, the models converged towards the X-ray structure. The averaged root mean square difference between the models and the X-ray structure is 1.26 and 1.75 Å for backbone atoms and all nonhydrogen atoms at the dimerization interface, respectively. The local helix–helix crossing angle of the X-ray structure falls within the range predicted by the models; a slight unwinding of the coiled coil toward the N-terminal DNA-binding end of the dimerization region has been correctly predicted. Distance maps between the helices are largely identical. The region around asparagine 20 is asymmetric in the X-structure and in the models. Surface side chain dihedrals showed a large variation in the models although the χ1, χ2, χ3, χ4 3-fold dihedrals were correctly predicted in 69, 42, 43, and 44% of the cases, respectively. Phenomenological free energies of dimerization of the models show little correlation with the root mean square difference between the models and the X-ray structure. © 1993 Wiley-Liss, Inc." @default.
• W2056911218 created "2016-06-24" @default.
• W2056911218 creator A5024276029 @default.
• W2056911218 creator A5056911622 @default.
• W2056911218 date "1993-02-01" @default.
• W2056911218 modified "2023-10-13" @default.
• W2056911218 title "Successful prediction of the coiled coil geometry of the GCN4 leucine zipper domain by simulated annealing: Comparison to the X-ray structure" @default.
• W2056911218 cites W1508596864 @default.
• W2056911218 cites W1543277803 @default.
• W2056911218 cites W1549740397 @default.
• W2056911218 cites W1971151709 @default.
• W2056911218 cites W1976499671 @default.
• W2056911218 cites W1979046104 @default.
• W2056911218 cites W1992323841 @default.
• W2056911218 cites W1993139876 @default.
• W2056911218 cites W1999271199 @default.
• W2056911218 cites W2004360551 @default.
• W2056911218 cites W2005393972 @default.
• W2056911218 cites W2008667021 @default.
• W2056911218 cites W2012334384 @default.
• W2056911218 cites W2027978582 @default.
• W2056911218 cites W2041189078 @default.
• W2056911218 cites W2044815019 @default.
• W2056911218 cites W2047891873 @default.
• W2056911218 cites W2052709323 @default.
• W2056911218 cites W2053621664 @default.
• W2056911218 cites W2055290772 @default.
• W2056911218 cites W2057691786 @default.
• W2056911218 cites W2063074006 @default.
• W2056911218 cites W2069142614 @default.
• W2056911218 cites W2072878092 @default.
• W2056911218 cites W2102697248 @default.
• W2056911218 cites W2115947396 @default.
• W2056911218 cites W2136567909 @default.
• W2056911218 cites W2158528894 @default.
• W2056911218 cites W2162166182 @default.
• W2056911218 cites W2619316257 @default.
• W2056911218 cites W4230223507 @default.
• W2056911218 doi "https://doi.org/10.1002/prot.340150205" @default.
• W2056911218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8441750" @default.
• W2056911218 hasPublicationYear "1993" @default.
• W2056911218 type Work @default.
• W2056911218 sameAs 2056911218 @default.
• W2056911218 citedByCount "67" @default.
• W2056911218 countsByYear W20569112182012 @default.
• W2056911218 countsByYear W20569112182014 @default.
• W2056911218 countsByYear W20569112182016 @default.
• W2056911218 crossrefType "journal-article" @default.
• W2056911218 hasAuthorship W2056911218A5024276029 @default.
• W2056911218 hasAuthorship W2056911218A5056911622 @default.
• W2056911218 hasConcept C104317684 @default.
• W2056911218 hasConcept C11413529 @default.
• W2056911218 hasConcept C121332964 @default.
• W2056911218 hasConcept C126980161 @default.
• W2056911218 hasConcept C156860981 @default.
• W2056911218 hasConcept C167625842 @default.
• W2056911218 hasConcept C185592680 @default.
• W2056911218 hasConcept C18903297 @default.
• W2056911218 hasConcept C2777855556 @default.
• W2056911218 hasConcept C2778530040 @default.
• W2056911218 hasConcept C2779965526 @default.
• W2056911218 hasConcept C33923547 @default.
• W2056911218 hasConcept C47701112 @default.
• W2056911218 hasConcept C55493867 @default.
• W2056911218 hasConcept C55988834 @default.
• W2056911218 hasConcept C62520636 @default.
• W2056911218 hasConcept C71907059 @default.
• W2056911218 hasConcept C8010536 @default.
• W2056911218 hasConcept C86803240 @default.
• W2056911218 hasConcept C97355855 @default.
• W2056911218 hasConceptScore W2056911218C104317684 @default.
• W2056911218 hasConceptScore W2056911218C11413529 @default.
• W2056911218 hasConceptScore W2056911218C121332964 @default.
• W2056911218 hasConceptScore W2056911218C126980161 @default.
• W2056911218 hasConceptScore W2056911218C156860981 @default.
• W2056911218 hasConceptScore W2056911218C167625842 @default.
• W2056911218 hasConceptScore W2056911218C185592680 @default.
• W2056911218 hasConceptScore W2056911218C18903297 @default.
• W2056911218 hasConceptScore W2056911218C2777855556 @default.
• W2056911218 hasConceptScore W2056911218C2778530040 @default.
• W2056911218 hasConceptScore W2056911218C2779965526 @default.
• W2056911218 hasConceptScore W2056911218C33923547 @default.
• W2056911218 hasConceptScore W2056911218C47701112 @default.
• W2056911218 hasConceptScore W2056911218C55493867 @default.
• W2056911218 hasConceptScore W2056911218C55988834 @default.
• W2056911218 hasConceptScore W2056911218C62520636 @default.
• W2056911218 hasConceptScore W2056911218C71907059 @default.
• W2056911218 hasConceptScore W2056911218C8010536 @default.
• W2056911218 hasConceptScore W2056911218C86803240 @default.
• W2056911218 hasConceptScore W2056911218C97355855 @default.
• W2056911218 hasIssue "2" @default.
• W2056911218 hasLocation W20569112181 @default.
• W2056911218 hasLocation W20569112182 @default.
• W2056911218 hasOpenAccess W2056911218 @default.
• W2056911218 hasPrimaryLocation W20569112181 @default.
• W2056911218 hasRelatedWork W119875627 @default.
• W2056911218 hasRelatedWork W1988350384 @default.
• W2056911218 hasRelatedWork W1989504189 @default.

• next