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- W2056961569 abstract "Macroconidia of a high-zearalenone-yieldingFusarium graminearum, NRRL 3198, were exposed to uv radiation and 0.02% nitrosoguanidine. The organism was also serially transferred in malt extract broth for up to 10 transfers. High proportions of morphologically distinctive low-toxin-producing variants (RUP variants) were isolated via unstable intermediates after mutagen treatments. The unstable intermediates readily reverted to high zearalenone producers with wild-type morphology. Stable RUP variants and more degenerate isolates (PR variants) were isolated in large numbers from the serial transfer experiments. Stable RUP variants did not revert to wild type even after uv exposure. Wild-type and RUP auxotrophs showed no reassortment in a heterokaryon test, implying that the RUP variants were not cytoplasmic mutants of NRRL 3198. Toxin production appeared to be augmented inWT/RUPheterokaryons despite the overall RUP morphologies of these cultures. Experiments with a further toxigenic and a nontoxigenic strain demonstrated that the lability found in NRRL 3198 was not common to all strains ofFusarium graminearum." @default.
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- W2056961569 date "1985-06-01" @default.
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- W2056961569 title "Degeneration of zearalenone production inFusarium graminearum" @default.
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- W2056961569 doi "https://doi.org/10.1016/0147-5975(85)90033-7" @default.
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