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- W2056994270 abstract "1multidisciplinary approaches have been directed toward minimizing spinal cord ischemic injury during surgery of the descending thoracic and thoracoabdominal aorta. The principal modality has been distal aortic perfusion during the aortic crossclamping, which was passive in the past with a temporary shunt tube or bypass and that currently has been active with a left heart bypass or a cardiopulmonary bypass (CPB). Other approaches include the following: intraoperative monitoring of spinal cord ischemia with somatosensory evoked potentials and transcranial motor evoked potentials; reattaching the responsible intercostal artery; increasing collateral fl ow by controlling the back-bleeding of the patent intercostal arteries with high cardiac output and arterial pressures with cerebrospinal fl uid (CSF) drainage; increasing ischemic tolerance with pharmacological adjuncts including naloxane, steroid, barbiturates, and with hypothermia; reducing excitotocixity from neuronal ischemia with hypothermia, naloxane, and steroid; and attenuating reperfusion injury with steroid, hypothermia, and free radical scavengers. Particularly, in Japan, with recent great advances in diagnostic imaging modalities, preoperative demonstration of the arteria radicularis magna (Adamkiewicz artery) by magnetic resonance imaging (MRI) or computed tomography (CT) scans has been highlighted as a reliable guide for reattachment or preservation of the responsible intercostal arteries including the collaterals. Since the 1950s hypothermia has been proven effective for protecting organs, including the central nervous system, in the cardiovascular surgical fi eld. 2–5 When focusing on milestones of aortic surgery, systemic profound hypothermia at 12°–15°C was applied to aortic arch surgery for brain protection in 1975. 6" @default.
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- W2056994270 date "2010-05-01" @default.
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- W2056994270 title "Is hypothermia a reliable adjunct for spinal cord protection in descending and thoracoabdominal aortic repair with regional or systemic cooling?" @default.
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- W2056994270 doi "https://doi.org/10.1007/s11748-009-0530-1" @default.
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