FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057006842> ?p ?o ?g. }

• W2057006842 endingPage "358" @default.
• W2057006842 startingPage "352" @default.
• W2057006842 abstract "Brevetoxins, the algal toxins produced by Karenia brevis during red tide blooms, adversely impact health following ingestion or inhalation. Inhalation of brevetoxins results in a variety of acute symptoms including coughing, wheezing, and shortness of breath. Analysis of manatee lungs following death by purported brevetoxicosis has identified brevetoxin accumulation within macrophages, with pathological manifestions of lung congestion, inflammation, and edema. The goals of this work were to specifically examine effects of brevetoxin-2 on alveolar macrophages, a key cell in responding to toxins in the lung, as well as to determine if brevetoxin-2 results in an inflammatory response and/or direct cytotoxicity. Exposure of an alveolar macrophage cell line (MH-S) to an environmentally and physiologically relevant dose of brevetoxin-2 (0.5 μg/ml) did not significantly alter cellular growth over a 24 h time period. However, exposure of MH-S cells to brevetoxin-2 for 6 h increased phagocytosis of latex beads, increased secretion of interleukin (IL)-2, IL-4, and tumor necrosis factor-α, and decreased secretion of IL-5. Very few changes were seen in gene expression following 3 or 6 h exposure to brevetoxin-2. These results show that brevetoxin-2 induced an immune response indicative of inflammation in an alveolar macrophage cell line, indicating that inhalation of brevetoxin-2 may lead to lung inflammation through an alveolar macrophage-initiated pathway." @default.
• W2057006842 created "2016-06-24" @default.
• W2057006842 creator A5002344510 @default.
• W2057006842 creator A5019244234 @default.
• W2057006842 date "2010-09-01" @default.
• W2057006842 modified "2023-09-25" @default.
• W2057006842 title "Brevetoxin-2 induces an inflammatory response in an alveolar macrophage cell line" @default.
• W2057006842 cites W1653545152 @default.
• W2057006842 cites W1735272425 @default.
• W2057006842 cites W1923917571 @default.
• W2057006842 cites W1947466829 @default.
• W2057006842 cites W1981516723 @default.
• W2057006842 cites W1992524269 @default.
• W2057006842 cites W1993587337 @default.
• W2057006842 cites W1998902445 @default.
• W2057006842 cites W2002797282 @default.
• W2057006842 cites W2008308371 @default.
• W2057006842 cites W2036308145 @default.
• W2057006842 cites W2041012467 @default.
• W2057006842 cites W2042204487 @default.
• W2057006842 cites W2073295417 @default.
• W2057006842 cites W2076833412 @default.
• W2057006842 cites W2082697116 @default.
• W2057006842 cites W2089676828 @default.
• W2057006842 cites W2094222003 @default.
• W2057006842 cites W2099928486 @default.
• W2057006842 cites W2101947072 @default.
• W2057006842 cites W2103017472 @default.
• W2057006842 cites W2104503250 @default.
• W2057006842 cites W2106073690 @default.
• W2057006842 cites W2114710210 @default.
• W2057006842 cites W2115993724 @default.
• W2057006842 cites W2120064570 @default.
• W2057006842 cites W2120640870 @default.
• W2057006842 cites W2123455971 @default.
• W2057006842 cites W2131969570 @default.
• W2057006842 cites W2147921065 @default.
• W2057006842 cites W2161605623 @default.
• W2057006842 cites W3023923910 @default.
• W2057006842 cites W4233953738 @default.
• W2057006842 cites W4254751786 @default.
• W2057006842 cites W4255291146 @default.
• W2057006842 doi "https://doi.org/10.1016/j.ijheh.2010.06.007" @default.
• W2057006842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20655277" @default.
• W2057006842 hasPublicationYear "2010" @default.
• W2057006842 type Work @default.
• W2057006842 sameAs 2057006842 @default.
• W2057006842 citedByCount "12" @default.
• W2057006842 countsByYear W20570068422012 @default.
• W2057006842 countsByYear W20570068422013 @default.
• W2057006842 countsByYear W20570068422017 @default.
• W2057006842 countsByYear W20570068422018 @default.
• W2057006842 countsByYear W20570068422022 @default.
• W2057006842 countsByYear W20570068422023 @default.
• W2057006842 crossrefType "journal-article" @default.
• W2057006842 hasAuthorship W2057006842A5002344510 @default.
• W2057006842 hasAuthorship W2057006842A5019244234 @default.
• W2057006842 hasConcept C134018914 @default.
• W2057006842 hasConcept C160448771 @default.
• W2057006842 hasConcept C164027704 @default.
• W2057006842 hasConcept C17991360 @default.
• W2057006842 hasConcept C202751555 @default.
• W2057006842 hasConcept C203014093 @default.
• W2057006842 hasConcept C2776914184 @default.
• W2057006842 hasConcept C2778012055 @default.
• W2057006842 hasConcept C2779244956 @default.
• W2057006842 hasConcept C49039625 @default.
• W2057006842 hasConcept C55493867 @default.
• W2057006842 hasConcept C86803240 @default.
• W2057006842 hasConcept C89423630 @default.
• W2057006842 hasConcept C98274493 @default.
• W2057006842 hasConceptScore W2057006842C134018914 @default.
• W2057006842 hasConceptScore W2057006842C160448771 @default.
• W2057006842 hasConceptScore W2057006842C164027704 @default.
• W2057006842 hasConceptScore W2057006842C17991360 @default.
• W2057006842 hasConceptScore W2057006842C202751555 @default.
• W2057006842 hasConceptScore W2057006842C203014093 @default.
• W2057006842 hasConceptScore W2057006842C2776914184 @default.
• W2057006842 hasConceptScore W2057006842C2778012055 @default.
• W2057006842 hasConceptScore W2057006842C2779244956 @default.
• W2057006842 hasConceptScore W2057006842C49039625 @default.
• W2057006842 hasConceptScore W2057006842C55493867 @default.
• W2057006842 hasConceptScore W2057006842C86803240 @default.
• W2057006842 hasConceptScore W2057006842C89423630 @default.
• W2057006842 hasConceptScore W2057006842C98274493 @default.
• W2057006842 hasIssue "5" @default.
• W2057006842 hasLocation W20570068421 @default.
• W2057006842 hasLocation W20570068422 @default.
• W2057006842 hasOpenAccess W2057006842 @default.
• W2057006842 hasPrimaryLocation W20570068421 @default.
• W2057006842 hasRelatedWork W1831485333 @default.
• W2057006842 hasRelatedWork W1972859816 @default.
• W2057006842 hasRelatedWork W2024431897 @default.
• W2057006842 hasRelatedWork W2142484500 @default.
• W2057006842 hasRelatedWork W2187766237 @default.
• W2057006842 hasRelatedWork W2330161102 @default.
• W2057006842 hasRelatedWork W2467958286 @default.
• W2057006842 hasRelatedWork W2689866037 @default.

• next