FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057043356> ?p ?o ?g. }

• W2057043356 abstract "Eleven chinchillas between 1 and 2.4 years of age had the malleus/incus complex removed from one middle ear and then lived in the Washington University animal facilities for 4 years post-surgery. Each animal had one ear (termed ambient-noise) in which the conductive apparatus was intact; the other ear (termed noise-protected) had a 50-60 dB conductive hearing loss. The background sound level in the animal facility was 59 dBA with periodic brief sounds up to 102 dBA. After the 4-year experimental period, both ears were fixed, embedded in plastic and dissected for microscopic examination as flat preparations. The quantitative and qualitative findings in the noise-protected ears were compared to those in the ambient-noise ears. Both groups of ears sustained losses of sensory and supporting cells throughout the organ of Corti. A variable amount of age pigment was found to have accumulated in the outer hair cells and all supporting cells. In the noise-protected ears, inner hair cell loss ranged from 1.0 to 3.1% and averaged 1.7 +/- 0.8%; outer hair cell loss ranged from 1.8 to 6.4% and averaged 3.6 +/- 1.2%. In the ambient-noise ears, inner hair cell loss ranged from 0.7 to 2.8% and averaged 1.6 +/- 0.7%; outer hair cell loss ranged from 1.3 to 5.4% and averaged 3.6 +/- 1.2%. Within-animal comparison of cell losses in the noise-protected and ambient-noise ears revealed no significant difference between the two groups. It is concluded that long-term exposure to micro-noise does not accelerate the spontaneous loss of sensory cells which occurs with aging. Although not quantified, there was no obvious difference in the amount or cellular distribution of age pigment in the two groups. Thus, it appears that the formation of age pigment in the ear is the result of the cells' basic metabolic processes rather than the wear and tear from sensory transduction." @default.
• W2057043356 created "2016-06-24" @default.
• W2057043356 creator A5017712004 @default.
• W2057043356 creator A5050176967 @default.
• W2057043356 creator A5078064383 @default.
• W2057043356 creator A5082812330 @default.
• W2057043356 date "1998-10-01" @default.
• W2057043356 modified "2023-09-24" @default.
• W2057043356 title "The role of micro-noise trauma in the etiology of aging-related changes in the inner ear" @default.
• W2057043356 cites W1536644186 @default.
• W2057043356 cites W1562148859 @default.
• W2057043356 cites W1572703898 @default.
• W2057043356 cites W157979716 @default.
• W2057043356 cites W1582872727 @default.
• W2057043356 cites W166381918 @default.
• W2057043356 cites W1969481534 @default.
• W2057043356 cites W1976449758 @default.
• W2057043356 cites W1976723773 @default.
• W2057043356 cites W1978397402 @default.
• W2057043356 cites W1979537760 @default.
• W2057043356 cites W1984887488 @default.
• W2057043356 cites W1991621972 @default.
• W2057043356 cites W1992119101 @default.
• W2057043356 cites W1992171268 @default.
• W2057043356 cites W2004774625 @default.
• W2057043356 cites W2007307878 @default.
• W2057043356 cites W2009556771 @default.
• W2057043356 cites W2017822067 @default.
• W2057043356 cites W2026011448 @default.
• W2057043356 cites W2030372710 @default.
• W2057043356 cites W2033388440 @default.
• W2057043356 cites W2037296578 @default.
• W2057043356 cites W2046326628 @default.
• W2057043356 cites W2052955641 @default.
• W2057043356 cites W2064031568 @default.
• W2057043356 cites W2078206309 @default.
• W2057043356 cites W2082259830 @default.
• W2057043356 cites W2089086832 @default.
• W2057043356 cites W2089735622 @default.
• W2057043356 cites W2105969341 @default.
• W2057043356 cites W2148513193 @default.
• W2057043356 cites W2198831759 @default.
• W2057043356 cites W2206330040 @default.
• W2057043356 cites W2274092188 @default.
• W2057043356 cites W2313045587 @default.
• W2057043356 cites W2320204433 @default.
• W2057043356 cites W2321855583 @default.
• W2057043356 cites W2323177602 @default.
• W2057043356 cites W2325194739 @default.
• W2057043356 cites W2406229281 @default.
• W2057043356 cites W2411429672 @default.
• W2057043356 cites W2414473759 @default.
• W2057043356 cites W2434809529 @default.
• W2057043356 cites W3197341078 @default.
• W2057043356 cites W573532387 @default.
• W2057043356 doi "https://doi.org/10.1016/s0378-5955(98)00132-4" @default.
• W2057043356 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9822911" @default.
• W2057043356 hasPublicationYear "1998" @default.
• W2057043356 type Work @default.
• W2057043356 sameAs 2057043356 @default.
• W2057043356 citedByCount "0" @default.
• W2057043356 crossrefType "journal-article" @default.
• W2057043356 hasAuthorship W2057043356A5017712004 @default.
• W2057043356 hasAuthorship W2057043356A5050176967 @default.
• W2057043356 hasAuthorship W2057043356A5078064383 @default.
• W2057043356 hasAuthorship W2057043356A5082812330 @default.
• W2057043356 hasConcept C105702510 @default.
• W2057043356 hasConcept C115961682 @default.
• W2057043356 hasConcept C154945302 @default.
• W2057043356 hasConcept C17743292 @default.
• W2057043356 hasConcept C2777846895 @default.
• W2057043356 hasConcept C2778006543 @default.
• W2057043356 hasConcept C2778500370 @default.
• W2057043356 hasConcept C2778585322 @default.
• W2057043356 hasConcept C2779260231 @default.
• W2057043356 hasConcept C2779356876 @default.
• W2057043356 hasConcept C2779365249 @default.
• W2057043356 hasConcept C2779415040 @default.
• W2057043356 hasConcept C2780493683 @default.
• W2057043356 hasConcept C2780650970 @default.
• W2057043356 hasConcept C2780659331 @default.
• W2057043356 hasConcept C3018332767 @default.
• W2057043356 hasConcept C41008148 @default.
• W2057043356 hasConcept C548259974 @default.
• W2057043356 hasConcept C71924100 @default.
• W2057043356 hasConcept C86803240 @default.
• W2057043356 hasConcept C99498987 @default.
• W2057043356 hasConceptScore W2057043356C105702510 @default.
• W2057043356 hasConceptScore W2057043356C115961682 @default.
• W2057043356 hasConceptScore W2057043356C154945302 @default.
• W2057043356 hasConceptScore W2057043356C17743292 @default.
• W2057043356 hasConceptScore W2057043356C2777846895 @default.
• W2057043356 hasConceptScore W2057043356C2778006543 @default.
• W2057043356 hasConceptScore W2057043356C2778500370 @default.
• W2057043356 hasConceptScore W2057043356C2778585322 @default.
• W2057043356 hasConceptScore W2057043356C2779260231 @default.
• W2057043356 hasConceptScore W2057043356C2779356876 @default.
• W2057043356 hasConceptScore W2057043356C2779365249 @default.
• W2057043356 hasConceptScore W2057043356C2779415040 @default.
• W2057043356 hasConceptScore W2057043356C2780493683 @default.

• next