FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057100786> ?p ?o ?g. }

• W2057100786 endingPage "1141" @default.
• W2057100786 startingPage "1136" @default.
• W2057100786 abstract "Background: Cardiac stem cell (CSC) dysfunction exists in various kinds of cardiovascular diseases, and may be responsible for the insufficient regeneration of cardiac myocytes and coronary vessels. However, whether chronic renal failure (CRF) affected CSC is unknown. Method: CRF was induced in adult male mice by 5/6 nephrectomy. The mice were killed at 12 weeks after operation. C-kit+ CSC numbers was evaluated by flow cytometer. Apoptosis and DNA damage of C-kit+ CSC in the control and CRF mice was analyzed by immunohistochemistry. In the in vitro study, normal medium, and medium with uremic rat serum were used for the CSC culture. Results: CSC counts attenuated significantly in the chronic renal failure model, whereas apoptosis cells and 8-OHdG-positive cells significantly increased. CSC derived form 5/6 nephrectomy mice showed an impaired anti-oxidant potential. In the cultured cells, CSCs subjected to uremic rat serum showed a higher frequency of TUNEL stain-positive and 8-OHdG-positive cells. The uremia rat serum reduced the expression of hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) in CSC. Conclusions: The current study elucidated that CSC number and function disorders existed in mice with chronic renal insufficiency. Apoptosis, oxidative stress and reduced angiogenic factors secretion caused by uremic toxins in serum are contributors to CSC dysfunction." @default.
• W2057100786 created "2016-06-24" @default.
• W2057100786 creator A5007399204 @default.
• W2057100786 creator A5008965185 @default.
• W2057100786 creator A5012321599 @default.
• W2057100786 creator A5020448010 @default.
• W2057100786 creator A5031028550 @default.
• W2057100786 creator A5041801347 @default.
• W2057100786 date "2013-07-23" @default.
• W2057100786 modified "2023-09-23" @default.
• W2057100786 title "Number and function impairment of resident C-Kit+ cardiac stem cells in mice with renal dysfunction caused by 5/6 nephrectomy" @default.
• W2057100786 cites W1983863109 @default.
• W2057100786 cites W1985365252 @default.
• W2057100786 cites W1991962444 @default.
• W2057100786 cites W2023754730 @default.
• W2057100786 cites W2026749151 @default.
• W2057100786 cites W2028036560 @default.
• W2057100786 cites W2041119309 @default.
• W2057100786 cites W2068906486 @default.
• W2057100786 cites W2086100170 @default.
• W2057100786 cites W2098312065 @default.
• W2057100786 cites W2099172135 @default.
• W2057100786 cites W2113516532 @default.
• W2057100786 cites W2117764442 @default.
• W2057100786 cites W2121408705 @default.
• W2057100786 cites W2121598143 @default.
• W2057100786 cites W2133808321 @default.
• W2057100786 cites W2135010444 @default.
• W2057100786 cites W2138936912 @default.
• W2057100786 cites W2153059526 @default.
• W2057100786 cites W2153859777 @default.
• W2057100786 cites W2153899938 @default.
• W2057100786 cites W2157271021 @default.
• W2057100786 cites W2168987491 @default.
• W2057100786 doi "https://doi.org/10.3109/0886022x.2013.815108" @default.
• W2057100786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23879535" @default.
• W2057100786 hasPublicationYear "2013" @default.
• W2057100786 type Work @default.
• W2057100786 sameAs 2057100786 @default.
• W2057100786 citedByCount "2" @default.
• W2057100786 countsByYear W20571007862015 @default.
• W2057100786 countsByYear W20571007862022 @default.
• W2057100786 crossrefType "journal-article" @default.
• W2057100786 hasAuthorship W2057100786A5007399204 @default.
• W2057100786 hasAuthorship W2057100786A5008965185 @default.
• W2057100786 hasAuthorship W2057100786A5012321599 @default.
• W2057100786 hasAuthorship W2057100786A5020448010 @default.
• W2057100786 hasAuthorship W2057100786A5031028550 @default.
• W2057100786 hasAuthorship W2057100786A5041801347 @default.
• W2057100786 hasBestOaLocation W20571007861 @default.
• W2057100786 hasConcept C126322002 @default.
• W2057100786 hasConcept C134018914 @default.
• W2057100786 hasConcept C142724271 @default.
• W2057100786 hasConcept C167734588 @default.
• W2057100786 hasConcept C170493617 @default.
• W2057100786 hasConcept C190283241 @default.
• W2057100786 hasConcept C2776151105 @default.
• W2057100786 hasConcept C2776635150 @default.
• W2057100786 hasConcept C2776996007 @default.
• W2057100786 hasConcept C2777025900 @default.
• W2057100786 hasConcept C2780091579 @default.
• W2057100786 hasConcept C2780227381 @default.
• W2057100786 hasConcept C2780972559 @default.
• W2057100786 hasConcept C28328180 @default.
• W2057100786 hasConcept C54355233 @default.
• W2057100786 hasConcept C55493867 @default.
• W2057100786 hasConcept C71924100 @default.
• W2057100786 hasConcept C86803240 @default.
• W2057100786 hasConceptScore W2057100786C126322002 @default.
• W2057100786 hasConceptScore W2057100786C134018914 @default.
• W2057100786 hasConceptScore W2057100786C142724271 @default.
• W2057100786 hasConceptScore W2057100786C167734588 @default.
• W2057100786 hasConceptScore W2057100786C170493617 @default.
• W2057100786 hasConceptScore W2057100786C190283241 @default.
• W2057100786 hasConceptScore W2057100786C2776151105 @default.
• W2057100786 hasConceptScore W2057100786C2776635150 @default.
• W2057100786 hasConceptScore W2057100786C2776996007 @default.
• W2057100786 hasConceptScore W2057100786C2777025900 @default.
• W2057100786 hasConceptScore W2057100786C2780091579 @default.
• W2057100786 hasConceptScore W2057100786C2780227381 @default.
• W2057100786 hasConceptScore W2057100786C2780972559 @default.
• W2057100786 hasConceptScore W2057100786C28328180 @default.
• W2057100786 hasConceptScore W2057100786C54355233 @default.
• W2057100786 hasConceptScore W2057100786C55493867 @default.
• W2057100786 hasConceptScore W2057100786C71924100 @default.
• W2057100786 hasConceptScore W2057100786C86803240 @default.
• W2057100786 hasIssue "8" @default.
• W2057100786 hasLocation W20571007861 @default.
• W2057100786 hasLocation W20571007862 @default.
• W2057100786 hasOpenAccess W2057100786 @default.
• W2057100786 hasPrimaryLocation W20571007861 @default.
• W2057100786 hasRelatedWork W1972216846 @default.
• W2057100786 hasRelatedWork W2003814064 @default.
• W2057100786 hasRelatedWork W2006996729 @default.
• W2057100786 hasRelatedWork W2007767297 @default.
• W2057100786 hasRelatedWork W2055444814 @default.
• W2057100786 hasRelatedWork W2072979799 @default.
• W2057100786 hasRelatedWork W2073034255 @default.

• next