Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057112809> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2057112809 endingPage "161" @default.
- W2057112809 startingPage "157" @default.
- W2057112809 abstract "Café-au-lait spots and neurofibromas are defining features of neurofibromatosis 1 (NF1), but they vary greatly in number, size, and clinical importance from patient to patient. The cause of this variability is unknown. We tested the hypotheses that development of these lesions is influenced by local or familial factors. The presence or absence of café-au-lait spots, cutaneous neurofibromas, and diffuse plexiform neurofibromas was recorded for each of 10 divisions of the body surface in 547 NF1 patients, including 117 affected individuals in 52 families. We used stratified Mantel-Haenszel tests to look for local associations between the presence of diffuse plexiform neurofibromas, cutaneous neurofibromas, and café-au-lait spots in individual body segments of NF1 patients. We used a random effects model to obtain intrafamilial correlation coefficients for the age-adjusted number of body divisions affected with each of the three lesions. No significant association was observed between the occurrence of cutaneous and diffuse plexiform neurofibromas, between café-au-lait spots and cutaneous neurofibromas, or between café-au-lait spots and plexiform neurofibromas in the same body segment. The correlation among relatives in the number of body segments affected with café-au-lait spots was 0.45 (95% confidence interval [CI] = 0.18–0.71), with cutaneous neurofibromas, 0.37 (95% CI = 0.15–0.55), and with plexiform neurofibromas, 0.35 (95% CI = 0.15–0.57). We conclude that the development of café-au-lait spots, cutaneous neurofibromas, and plexiform neurofibromas are spatially independent in NF1 patients but that the development of all three lesions is influenced by familial factors. © 2003 Wiley-Liss, Inc." @default.
- W2057112809 created "2016-06-24" @default.
- W2057112809 creator A5020713848 @default.
- W2057112809 creator A5026208658 @default.
- W2057112809 creator A5033104211 @default.
- W2057112809 creator A5039150884 @default.
- W2057112809 creator A5051852805 @default.
- W2057112809 date "2004-01-01" @default.
- W2057112809 modified "2023-09-27" @default.
- W2057112809 title "Analysis of neurofibromatosis 1 (NF1) lesions by body segment" @default.
- W2057112809 cites W1495338768 @default.
- W2057112809 cites W1954469448 @default.
- W2057112809 cites W2000690172 @default.
- W2057112809 cites W2001577233 @default.
- W2057112809 cites W2015730907 @default.
- W2057112809 cites W2033533375 @default.
- W2057112809 cites W2043056873 @default.
- W2057112809 cites W2047184199 @default.
- W2057112809 cites W2048140690 @default.
- W2057112809 cites W2055729102 @default.
- W2057112809 cites W2163393726 @default.
- W2057112809 cites W4253368897 @default.
- W2057112809 cites W4254962459 @default.
- W2057112809 cites W4255825445 @default.
- W2057112809 doi "https://doi.org/10.1002/ajmg.a.20354" @default.
- W2057112809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14981716" @default.
- W2057112809 hasPublicationYear "2004" @default.
- W2057112809 type Work @default.
- W2057112809 sameAs 2057112809 @default.
- W2057112809 citedByCount "13" @default.
- W2057112809 countsByYear W20571128092014 @default.
- W2057112809 countsByYear W20571128092017 @default.
- W2057112809 countsByYear W20571128092018 @default.
- W2057112809 crossrefType "journal-article" @default.
- W2057112809 hasAuthorship W2057112809A5020713848 @default.
- W2057112809 hasAuthorship W2057112809A5026208658 @default.
- W2057112809 hasAuthorship W2057112809A5033104211 @default.
- W2057112809 hasAuthorship W2057112809A5039150884 @default.
- W2057112809 hasAuthorship W2057112809A5051852805 @default.
- W2057112809 hasConcept C105702510 @default.
- W2057112809 hasConcept C142724271 @default.
- W2057112809 hasConcept C16005928 @default.
- W2057112809 hasConcept C2777831590 @default.
- W2057112809 hasConcept C2778695362 @default.
- W2057112809 hasConcept C2778984943 @default.
- W2057112809 hasConcept C2910078708 @default.
- W2057112809 hasConcept C71924100 @default.
- W2057112809 hasConceptScore W2057112809C105702510 @default.
- W2057112809 hasConceptScore W2057112809C142724271 @default.
- W2057112809 hasConceptScore W2057112809C16005928 @default.
- W2057112809 hasConceptScore W2057112809C2777831590 @default.
- W2057112809 hasConceptScore W2057112809C2778695362 @default.
- W2057112809 hasConceptScore W2057112809C2778984943 @default.
- W2057112809 hasConceptScore W2057112809C2910078708 @default.
- W2057112809 hasConceptScore W2057112809C71924100 @default.
- W2057112809 hasIssue "2" @default.
- W2057112809 hasLocation W20571128091 @default.
- W2057112809 hasLocation W20571128092 @default.
- W2057112809 hasOpenAccess W2057112809 @default.
- W2057112809 hasPrimaryLocation W20571128091 @default.
- W2057112809 hasRelatedWork W1491292261 @default.
- W2057112809 hasRelatedWork W196372489 @default.
- W2057112809 hasRelatedWork W2057112809 @default.
- W2057112809 hasRelatedWork W2073945322 @default.
- W2057112809 hasRelatedWork W2100182374 @default.
- W2057112809 hasRelatedWork W2301938706 @default.
- W2057112809 hasRelatedWork W3168398365 @default.
- W2057112809 hasRelatedWork W4224019516 @default.
- W2057112809 hasRelatedWork W60691048 @default.
- W2057112809 hasRelatedWork W1838530886 @default.
- W2057112809 hasVolume "125A" @default.
- W2057112809 isParatext "false" @default.
- W2057112809 isRetracted "false" @default.
- W2057112809 magId "2057112809" @default.
- W2057112809 workType "article" @default.