FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057113699> ?p ?o ?g. }

• W2057113699 endingPage "1143" @default.
• W2057113699 startingPage "1131" @default.
• W2057113699 abstract "We have characterized the monocarboxylate permease family of Saccharomyces cerevisiae comprising five proteins. We could not find any evidence that the monocarboxylate transporter-homologous (Mch) proteins of S. cerevisiae are involved in the uptake or secretion of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane. A yeast mutant strain deleted for all five MCH genes exhibited no growth defects on monocarboxylic acids as the sole carbon and energy sources. Moreover, the uptake and secretion rates of monocarboxylic acids were indistinguishable from the wild-type strain. Additional deletion of the JEN1 lactate transporter gene completely blocked uptake of lactate and pyruvate. However, uptake of acetate was not even affected after the additional deletion of the gene YHL008c, which had been proposed to code for an acetate transporter. The mch1-5 mutant strain showed strongly reduced biomass yields in aerobic glucose-limited chemostat cultures, pointing to the involvement of Mch transporters in mitochondrial metabolism. Indeed, intracellular localization studies indicated that at least some of the Mch proteins reside in intracellular membranes. However, pyruvate uptake into isolated mitochondria was not affected in the mch1-5 mutant strain. It is concluded that the yeast monocarboxylate transporter-homologous proteins perform other functions than do their mammalian counterparts." @default.
• W2057113699 created "2016-06-24" @default.
• W2057113699 creator A5016391062 @default.
• W2057113699 creator A5025910449 @default.
• W2057113699 creator A5045242501 @default.
• W2057113699 creator A5058026562 @default.
• W2057113699 creator A5064656627 @default.
• W2057113699 creator A5068117758 @default.
• W2057113699 creator A5081637493 @default.
• W2057113699 creator A5008228761 @default.
• W2057113699 date "2001-08-01" @default.
• W2057113699 modified "2023-10-16" @default.
• W2057113699 title "The putative monocarboxylate permeases of the yeast<i>Saccharomyces cerevisiae</i>do not transport monocarboxylic acids across the plasma membrane" @default.
• W2057113699 cites W1456663196 @default.
• W2057113699 cites W1488548087 @default.
• W2057113699 cites W1507851645 @default.
• W2057113699 cites W1533390549 @default.
• W2057113699 cites W1585201495 @default.
• W2057113699 cites W1845254999 @default.
• W2057113699 cites W1850569493 @default.
• W2057113699 cites W1933882513 @default.
• W2057113699 cites W1987433777 @default.
• W2057113699 cites W1998976350 @default.
• W2057113699 cites W2019870956 @default.
• W2057113699 cites W2041509866 @default.
• W2057113699 cites W2055337186 @default.
• W2057113699 cites W2056989675 @default.
• W2057113699 cites W2071416115 @default.
• W2057113699 cites W2079572055 @default.
• W2057113699 cites W2087269504 @default.
• W2057113699 cites W2101442503 @default.
• W2057113699 cites W2101447091 @default.
• W2057113699 cites W2104090158 @default.
• W2057113699 cites W2109318635 @default.
• W2057113699 cites W2114071827 @default.
• W2057113699 cites W2115422703 @default.
• W2057113699 cites W2124859343 @default.
• W2057113699 cites W2130381741 @default.
• W2057113699 cites W2138664060 @default.
• W2057113699 cites W2141627667 @default.
• W2057113699 cites W2145265114 @default.
• W2057113699 cites W2151258701 @default.
• W2057113699 doi "https://doi.org/10.1002/yea.763" @default.
• W2057113699 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11536335" @default.
• W2057113699 hasPublicationYear "2001" @default.
• W2057113699 type Work @default.
• W2057113699 sameAs 2057113699 @default.
• W2057113699 citedByCount "62" @default.
• W2057113699 countsByYear W20571136992012 @default.
• W2057113699 countsByYear W20571136992013 @default.
• W2057113699 countsByYear W20571136992014 @default.
• W2057113699 countsByYear W20571136992015 @default.
• W2057113699 countsByYear W20571136992016 @default.
• W2057113699 countsByYear W20571136992017 @default.
• W2057113699 countsByYear W20571136992019 @default.
• W2057113699 countsByYear W20571136992020 @default.
• W2057113699 countsByYear W20571136992022 @default.
• W2057113699 countsByYear W20571136992023 @default.
• W2057113699 crossrefType "journal-article" @default.
• W2057113699 hasAuthorship W2057113699A5008228761 @default.
• W2057113699 hasAuthorship W2057113699A5016391062 @default.
• W2057113699 hasAuthorship W2057113699A5025910449 @default.
• W2057113699 hasAuthorship W2057113699A5045242501 @default.
• W2057113699 hasAuthorship W2057113699A5058026562 @default.
• W2057113699 hasAuthorship W2057113699A5064656627 @default.
• W2057113699 hasAuthorship W2057113699A5068117758 @default.
• W2057113699 hasAuthorship W2057113699A5081637493 @default.
• W2057113699 hasBestOaLocation W20571136992 @default.
• W2057113699 hasConcept C104317684 @default.
• W2057113699 hasConcept C115335371 @default.
• W2057113699 hasConcept C143065580 @default.
• W2057113699 hasConcept C149011108 @default.
• W2057113699 hasConcept C190114821 @default.
• W2057113699 hasConcept C2777576037 @default.
• W2057113699 hasConcept C2779222958 @default.
• W2057113699 hasConcept C2781217356 @default.
• W2057113699 hasConcept C55493867 @default.
• W2057113699 hasConcept C86803240 @default.
• W2057113699 hasConceptScore W2057113699C104317684 @default.
• W2057113699 hasConceptScore W2057113699C115335371 @default.
• W2057113699 hasConceptScore W2057113699C143065580 @default.
• W2057113699 hasConceptScore W2057113699C149011108 @default.
• W2057113699 hasConceptScore W2057113699C190114821 @default.
• W2057113699 hasConceptScore W2057113699C2777576037 @default.
• W2057113699 hasConceptScore W2057113699C2779222958 @default.
• W2057113699 hasConceptScore W2057113699C2781217356 @default.
• W2057113699 hasConceptScore W2057113699C55493867 @default.
• W2057113699 hasConceptScore W2057113699C86803240 @default.
• W2057113699 hasIssue "12" @default.
• W2057113699 hasLocation W20571136991 @default.
• W2057113699 hasLocation W20571136992 @default.
• W2057113699 hasLocation W20571136993 @default.
• W2057113699 hasOpenAccess W2057113699 @default.
• W2057113699 hasPrimaryLocation W20571136991 @default.
• W2057113699 hasRelatedWork W1991454487 @default.
• W2057113699 hasRelatedWork W2025891680 @default.
• W2057113699 hasRelatedWork W2044577407 @default.
• W2057113699 hasRelatedWork W2078333270 @default.

• next