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- W2057114610 abstract "Celecoxib belongs to a new NSAID family specifically inhibiting cyclooxygenase‐2 (COX‐2). The present formulations require high dosage since the transmembrane transport fluctuates and is very difficult to control. We solubilized celecoxib in micelles of nonionic microemulsions and hydrophilic surfactant. The supersaturated solubilized drug was precipitated from the nano‐droplets to form a new solid structure with improved dissolution properties. The selected microemulsion systems loaded with celecoxib were characterized by SAXS, SD‐NMR, viscosity, and electrical conductivity techniques. Precipitation was conducted from W/O as well as from O/W U‐type microemulsions. The crystals obtained by the precipitation were characterized by x‐ray powder scattering, differential scanning calorimetry, FTIR measurements, and microscopic scans." @default.
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- W2057114610 date "2007-10-01" @default.
- W2057114610 modified "2023-09-24" @default.
- W2057114610 title "Crystallization of Celecoxib in Microemulsion Media" @default.
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- W2057114610 doi "https://doi.org/10.1080/01932690701528035" @default.
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