Matches in SemOpenAlex for { <https://semopenalex.org/work/W2057129372> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2057129372 endingPage "1720" @default.
- W2057129372 startingPage "1720" @default.
- W2057129372 abstract "It is not known whether the effects of desflurane on local cerebral glucose utilization (LCGU) and local cerebral blood flow (LCBF) are different from those of other volatile anesthetics.Using the autoradiographic iodoantipyrine and deoxyglucose methods, LCGU, LCBF, and their overall means were measured in 60 Sprague-Dawley rats (10 groups, n = 6 each) during desflurane and isoflurane anesthesia and in conscious controls.During anesthesia, mean cerebral glucose utilization was decreased compared with conscious controls: 1 minimum alveolar concentration (MAC) desflurane: -52%; 1 MAC isoflurane: -44%; 2 MAC desflurane: -62%; and 2 MAC isoflurane: -60%. Local analysis showed a reduction of LCGU in the majority of the 40 brain regions analyzed. Mean cerebral blood flow was increased: 1 MAC desflurane: +40%; 1 MAC isoflurane: +43%; 2 MAC desflurane and 2 MAC isoflurane: +70%. LCBF was increased in all brain structures investigated except in the auditory cortex. No significant differences (P < 0.05) could be observed between both anesthetics for mean values of cerebral glucose use and blood flow. Correlation coefficients obtained for the relation between LCGU and LCBF were as follows: controls: 0.95; 1 MAC desflurane: 0.89; 2 MAC desflurane: 0.60; 1 MAC isoflurane: 0.87; and 2 MAC isoflurane: 0.68.Differences in the physicochemical properties of desflurane compared with isoflurane are not associated with major differences in the effects of both volatile anesthetics on cerebral glucose utilization, blood flow, and the coupling between LCBF and LCGU." @default.
- W2057129372 created "2016-06-24" @default.
- W2057129372 creator A5030918082 @default.
- W2057129372 creator A5032410468 @default.
- W2057129372 creator A5034259480 @default.
- W2057129372 creator A5037694362 @default.
- W2057129372 creator A5042683887 @default.
- W2057129372 creator A5060455065 @default.
- W2057129372 creator A5083660340 @default.
- W2057129372 date "1999-12-01" @default.
- W2057129372 modified "2023-09-26" @default.
- W2057129372 title "Local Coupling of Cerebral Blood Flow to Cerebral Glucose Metabolism during Inhalational Anesthesia in Rats " @default.
- W2057129372 cites W1980993983 @default.
- W2057129372 cites W1981391377 @default.
- W2057129372 cites W1987773106 @default.
- W2057129372 cites W1988499936 @default.
- W2057129372 cites W1990547216 @default.
- W2057129372 cites W1991390696 @default.
- W2057129372 cites W1992493552 @default.
- W2057129372 cites W1996186792 @default.
- W2057129372 cites W1997834318 @default.
- W2057129372 cites W2001419018 @default.
- W2057129372 cites W2004943268 @default.
- W2057129372 cites W2012444248 @default.
- W2057129372 cites W2034683665 @default.
- W2057129372 cites W2039102675 @default.
- W2057129372 cites W2051039822 @default.
- W2057129372 cites W2072058482 @default.
- W2057129372 cites W2073926502 @default.
- W2057129372 cites W2077321554 @default.
- W2057129372 cites W2090306035 @default.
- W2057129372 cites W2092810960 @default.
- W2057129372 cites W2108990419 @default.
- W2057129372 cites W2110146562 @default.
- W2057129372 cites W2147760376 @default.
- W2057129372 cites W2160743951 @default.
- W2057129372 cites W2169142949 @default.
- W2057129372 cites W91346249 @default.
- W2057129372 doi "https://doi.org/10.1097/00000542-199912000-00025" @default.
- W2057129372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10598615" @default.
- W2057129372 hasPublicationYear "1999" @default.
- W2057129372 type Work @default.
- W2057129372 sameAs 2057129372 @default.
- W2057129372 citedByCount "41" @default.
- W2057129372 countsByYear W20571293722013 @default.
- W2057129372 countsByYear W20571293722014 @default.
- W2057129372 countsByYear W20571293722016 @default.
- W2057129372 countsByYear W20571293722017 @default.
- W2057129372 countsByYear W20571293722018 @default.
- W2057129372 countsByYear W20571293722019 @default.
- W2057129372 countsByYear W20571293722021 @default.
- W2057129372 countsByYear W20571293722022 @default.
- W2057129372 crossrefType "journal-article" @default.
- W2057129372 hasAuthorship W2057129372A5030918082 @default.
- W2057129372 hasAuthorship W2057129372A5032410468 @default.
- W2057129372 hasAuthorship W2057129372A5034259480 @default.
- W2057129372 hasAuthorship W2057129372A5037694362 @default.
- W2057129372 hasAuthorship W2057129372A5042683887 @default.
- W2057129372 hasAuthorship W2057129372A5060455065 @default.
- W2057129372 hasAuthorship W2057129372A5083660340 @default.
- W2057129372 hasBestOaLocation W20571293721 @default.
- W2057129372 hasConcept C157767197 @default.
- W2057129372 hasConcept C2776359302 @default.
- W2057129372 hasConcept C2776442465 @default.
- W2057129372 hasConcept C2776954882 @default.
- W2057129372 hasConcept C2777011798 @default.
- W2057129372 hasConcept C2781453256 @default.
- W2057129372 hasConcept C42219234 @default.
- W2057129372 hasConcept C71924100 @default.
- W2057129372 hasConceptScore W2057129372C157767197 @default.
- W2057129372 hasConceptScore W2057129372C2776359302 @default.
- W2057129372 hasConceptScore W2057129372C2776442465 @default.
- W2057129372 hasConceptScore W2057129372C2776954882 @default.
- W2057129372 hasConceptScore W2057129372C2777011798 @default.
- W2057129372 hasConceptScore W2057129372C2781453256 @default.
- W2057129372 hasConceptScore W2057129372C42219234 @default.
- W2057129372 hasConceptScore W2057129372C71924100 @default.
- W2057129372 hasIssue "6" @default.
- W2057129372 hasLocation W20571293721 @default.
- W2057129372 hasLocation W20571293722 @default.
- W2057129372 hasOpenAccess W2057129372 @default.
- W2057129372 hasPrimaryLocation W20571293721 @default.
- W2057129372 hasRelatedWork W1963943943 @default.
- W2057129372 hasRelatedWork W1991924015 @default.
- W2057129372 hasRelatedWork W2011803841 @default.
- W2057129372 hasRelatedWork W2061377660 @default.
- W2057129372 hasRelatedWork W2081918364 @default.
- W2057129372 hasRelatedWork W2100814309 @default.
- W2057129372 hasRelatedWork W2116679129 @default.
- W2057129372 hasRelatedWork W2148545167 @default.
- W2057129372 hasRelatedWork W2159075352 @default.
- W2057129372 hasRelatedWork W2168202526 @default.
- W2057129372 hasVolume "91" @default.
- W2057129372 isParatext "false" @default.
- W2057129372 isRetracted "false" @default.
- W2057129372 magId "2057129372" @default.
- W2057129372 workType "article" @default.