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• W2057142006 abstract "The treatment of preterm newborn rabbits with synthetic surfactants containing simple phospholipid mixtures and peptides gives similar tidal volumes to treatment with poractant alfa (Curosurf®). The addition of both surfactant protein B and C analogs to the phospholipid mixture will stabilize the alveoli, measured as lung gas volumes at end expiration, even if no positive end-expiratory pressure is applied. The effect on lung gas volumes seems to depend on the structure of the peptides as well as the phospholipid composition. It seems that synthetic surfactants containing two peptides and a more complex phospholipid composition will be able to replace natural surfactants within the near future, but more experiments need to be performed before any conclusion can be drawn about the ideal composition of this new generation of synthetic surfactants." @default.
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• W2057142006 date "2013-01-01" @default.
• W2057142006 modified "2023-10-01" @default.
• W2057142006 title "New Generation Synthetic Surfactants" @default.
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• W2057142006 doi "https://doi.org/10.1159/000349942" @default.
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